BS6534

antibody from Bioworld Technology, Inc
Targeting: BMPR1B ALK6, CDw293
Provider product page for BS6534
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6534 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BMPR1B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human BMPR1B.
Description
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BMPR1B protein structure - BS6534 shown in red.