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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- MAB505-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Mouse BMPR-IB/ALK-6 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human and mouse BMPR-IB/ALK-6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse (rm) BMPR-IB and no cross-reactivity with recombinant human (rh) BMPR-IA, rmBMPR-IA, or rhBMPR-II is observed.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 88614
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection.
A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7.
Regulation of bone morphogenetic protein signalling in human pulmonary vascular development.
Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia.
Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach.
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism.
Beckham JD, Tuttle K, Tyler KL
Journal of virology 2009 May;83(10):5035-45
Journal of virology 2009 May;83(10):5035-45
A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7.
Sengle G, Ono RN, Lyons KM, Bächinger HP, Sakai LY
Journal of molecular biology 2008 Sep 12;381(4):1025-39
Journal of molecular biology 2008 Sep 12;381(4):1025-39
Regulation of bone morphogenetic protein signalling in human pulmonary vascular development.
Southwood M, Jeffery TK, Yang X, Upton PD, Hall SM, Atkinson C, Haworth SG, Stewart S, Reynolds PN, Long L, Trembath RC, Morrell NW
The Journal of pathology 2008 Jan;214(1):85-95
The Journal of pathology 2008 Jan;214(1):85-95
Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia.
Alejandre-Alcázar MA, Kwapiszewska G, Reiss I, Amarie OV, Marsh LM, Sevilla-Pérez J, Wygrecka M, Eul B, Köbrich S, Hesse M, Schermuly RT, Seeger W, Eickelberg O, Morty RE
American journal of physiology. Lung cellular and molecular physiology 2007 Feb;292(2):L537-49
American journal of physiology. Lung cellular and molecular physiology 2007 Feb;292(2):L537-49
Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach.
Bleuming SA, Kodach LL, Garcia Leon MJ, Richel DJ, Peppelenbosch MP, Reitsma PH, Hardwick JC, van den Brink GR
The Journal of pathology 2006 Jun;209(2):190-7
The Journal of pathology 2006 Jun;209(2):190-7
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism.
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET
Cancer research 2005 Sep 15;65(18):8274-85
Cancer research 2005 Sep 15;65(18):8274-85
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