Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- AF505 - Provider product page
- Provider
- R&D Systems
- Product name
- Human BMPR-IB/ALK-6 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human BMPR-IB in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse BMPR-IB is observed and less than 1% cross-reactivity with recombinant human (rh) BMPR-IA and rhBMPR-II is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
O00238
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity.
Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro.
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors.
Cao Y, Slaney CY, Bidwell BN, Parker BS, Johnstone CN, Rautela J, Eckhardt BL, Anderson RL
Cancer research 2014 Sep 15;74(18):5091-102
Cancer research 2014 Sep 15;74(18):5091-102
Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro.
Fong D, Bisson M, Laberge G, McManus S, Grenier G, Faucheux N, Roux S
Cellular signalling 2013 Apr;25(4):717-28
Cellular signalling 2013 Apr;25(4):717-28
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.
Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, Kim M, Totonchy M, Cusack T, Ene C, Ma H, Su Q, Zenklusen JC, Zhang W, Maric D, Fine HA
Cancer cell 2008 Jan;13(1):69-80
Cancer cell 2008 Jan;13(1):69-80
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors.
Pi X, Ren R, Kelley R, Zhang C, Moser M, Bohil AB, Divito M, Cheney RE, Patterson C
The Journal of cell biology 2007 Dec 31;179(7):1569-82
The Journal of cell biology 2007 Dec 31;179(7):1569-82
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