ABIN310967

antibody from antibodies-online

Targeting: DKK1 DKK-1, SK

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN310967

Provider

antibodies-online

Product name

anti-Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-DKK1 antibody: synthetic peptide directed towards the C terminal of human DKK1

Description

Protein A purified

Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Porcine, Rabbit, Xenopus, Zebrafish

Host

Rabbit

Antigen sequence

CARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQ
RCYCG EGLSCRIQKD


Epitope

C-Term

Vial size

100 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling.

Ai M, Holmen SL, Van Hul W, Williams BO, Warman ML
Molecular and cellular biology 2005 Jun;25(12):4946-55