RA0183

antibody from Oursmab
Targeting: DKK1 DKK-1, SK
Provider product page for RA0183
Western blot
ELISA
Immunocytochemistry
Flow cytometry
Functional assay

Antibody data

Product number
RA0183 - Provider product page
Provider
Oursmab
Product name
Sirexatamab (Biosimilar Reference Antibody) (DKK1)
Antibody type
Monoclonal
Description
Sirexatamab is a humanized IgG4 monoclonal antibody targeting Dickkopf-related protein 1 (DKK1), a secreted inhibitor of the Wnt/¦Â-catenin signaling pathway. By binding to and neutralizing DKK1, it restores Wnt pathway activity, promoting bone formation and potentially modulating tumor microenvironment signaling. It is being developed for the treatment of bone metastatic cancers (e.g., prostate, breast cancer) and osteolytic bone diseases.
Reactivity
Human
Isotype
IgG
Vial size
100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
Concentration
Bottled at the concentration indicated on the vial.
Storage
Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
DKK1 protein structure - RA0183 shown in red.