Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- MAB10962 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human Dkk-1 Monoclonal Antibody (Clone 141135)
- Antibody type
- Monoclonal
- Antigen
- S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Dkk-1, Thr32-His266
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
O94907
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Decreased osteogenesis, increased cell senescence and elevated Dickkopf-1 secretion in human fracture non union stromal cells.
Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment.
Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma.
Bajada S, Marshall MJ, Wright KT, Richardson JB, Johnson WE
Bone 2009 Oct;45(4):726-35
Bone 2009 Oct;45(4):726-35
Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment.
Heider U, Kaiser M, Mieth M, Lamottke B, Rademacher J, Jakob C, Braendle E, Stover D, Sezer O
European journal of haematology 2009 Jan;82(1):31-8
European journal of haematology 2009 Jan;82(1):31-8
Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma.
Qiang YW, Chen Y, Stephens O, Brown N, Chen B, Epstein J, Barlogie B, Shaughnessy JD Jr
Blood 2008 Jul 1;112(1):196-207
Blood 2008 Jul 1;112(1):196-207
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