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- Antigen structure
- References [14]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 21633-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21633-1-AP, RRID:AB_10793666
- Product name
- MAP1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MAP1B antibody (Cat. #21633-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification and validation of a signature based on myofibroblastic cancer-associated fibroblast marker genes for predicting prognosis, immune infiltration, and therapeutic response in bladder cancer.
Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons.
Leucine-rich repeat kinase 2 (LRRK2) inhibition upregulates microtubule-associated protein 1B to ameliorate lysosomal dysfunction and parkinsonism.
Endothelin-1, over-expressed in SOD1(G93A) mice, aggravates injury of NSC34-hSOD1G93A cells through complicated molecular mechanism revealed by quantitative proteomics analysis.
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model.
FMRP and MOV10 regulate Dicer1 expression and dendrite development.
Microtubule-associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in spinal muscular atrophy.
FMRP-absence-induced up-regulation of hypothalamic MAP1B expression decreases AgRP level linking with reduces in food intake and body weight.
Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.
MAP1B-LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules.
eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability.
GIT1 enhances neurite outgrowth by stimulating microtubule assembly.
Qin R, Ma X, Pu S, Shen C, Hu D, Liu C, Wang K, Wang Y
Investigative and clinical urology 2024 May;65(3):263-278
Investigative and clinical urology 2024 May;65(3):263-278
Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons.
Garone MG, Salerno D, Rosa A
Cell death discovery 2023 Jan 26;9(1):33
Cell death discovery 2023 Jan 26;9(1):33
Leucine-rich repeat kinase 2 (LRRK2) inhibition upregulates microtubule-associated protein 1B to ameliorate lysosomal dysfunction and parkinsonism.
Chen K, Tang F, Du B, Yue ZZ, Jiao LL, Ding XL, Tuo QZ, Meng J, He SY, Dai L, Lei P, Wei XW
MedComm 2023 Dec;4(6):e429
MedComm 2023 Dec;4(6):e429
Endothelin-1, over-expressed in SOD1(G93A) mice, aggravates injury of NSC34-hSOD1G93A cells through complicated molecular mechanism revealed by quantitative proteomics analysis.
Zhang Y, Chen L, Li Z, Li D, Wu Y, Guo Y
Frontiers in cellular neuroscience 2022;16:1069617
Frontiers in cellular neuroscience 2022;16:1069617
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
Strohm L, Hu Z, Suk Y, Rühmkorf A, Sternburg E, Gattringer V, Riemenschneider H, Berutti R, Graf E, Weishaupt JH, Brill MS, Harbauer AB, Dormann D, Dengjel J, Edbauer D, Behrends C
Life science alliance 2022 Nov;5(11)
Life science alliance 2022 Nov;5(11)
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model.
Zobaroğlu Özer P, Koyunoğlu D, Son ÇD, Erdem-Yurter H, Bora G
Molecular and cellular neurosciences 2022 May;120:103725
Molecular and cellular neurosciences 2022 May;120:103725
FMRP and MOV10 regulate Dicer1 expression and dendrite development.
Lannom MC, Nielsen J, Nawaz A, Shilikbay T, Ceman S
PloS one 2021;16(11):e0260005
PloS one 2021;16(11):e0260005
Microtubule-associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in spinal muscular atrophy.
Bora G, Hensel N, Rademacher S, Koyunoğlu D, Sunguroğlu M, Aksu-Mengeş E, Balcı-Hayta B, Claus P, Erdem-Yurter H
Human molecular genetics 2021 Feb 25;29(24):3935-3944
Human molecular genetics 2021 Feb 25;29(24):3935-3944
FMRP-absence-induced up-regulation of hypothalamic MAP1B expression decreases AgRP level linking with reduces in food intake and body weight.
Long JY, Jiang W, Xia HB, Fu JY, Lu P, Hu F, Feng WC, Sun WW, Gao MM, Yi YH, Long YS
Neurochemistry international 2020 Nov;140:104847
Neurochemistry international 2020 Nov;140:104847
Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.
Cui L, Zheng J, Zhao Q, Chen JR, Liu H, Peng G, Wu Y, Chen C, He Q, Shi H, Yin S, Friedman RA, Chen Y, Guan MX
JCI insight 2020 Dec 3;5(23)
JCI insight 2020 Dec 3;5(23)
MAP1B-LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules.
Arasaki K, Nagashima H, Kurosawa Y, Kimura H, Nishida N, Dohmae N, Yamamoto A, Yanagi S, Wakana Y, Inoue H, Tagaya M
EMBO reports 2018 Aug;19(8)
EMBO reports 2018 Aug;19(8)
eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Heise C, Taha E, Murru L, Ponzoni L, Cattaneo A, Guarnieri FC, Montani C, Mossa A, Vezzoli E, Ippolito G, Zapata J, Barrera I, Ryazanov AG, Cook J, Poe M, Stephen MR, Kopanitsa M, Benfante R, Rusconi F, Braida D, Francolini M, Proud CG, Valtorta F, Passafaro M, Sala M, Bachi A, Verpelli C, Rosenblum K, Sala C
Cerebral cortex (New York, N.Y. : 1991) 2017 Mar 1;27(3):2226-2248
Cerebral cortex (New York, N.Y. : 1991) 2017 Mar 1;27(3):2226-2248
Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability.
Wu J, He Z, Wang DL, Sun FL
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2980-2991
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2980-2991
GIT1 enhances neurite outgrowth by stimulating microtubule assembly.
Li YS, Qin LX, Liu J, Xia WL, Li JP, Shen HL, Gao WQ
Neural regeneration research 2016 Mar;11(3):427-34
Neural regeneration research 2016 Mar;11(3):427-34
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 21633-1-AP(MAP1B antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAP1B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MAP1B. This antibody recognizes human,mouse,rat antigen. The MAP1B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
