Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 21633-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21633-1-AP, RRID:AB_10793666
- Product name
- MAP1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MAP1B antibody (Cat. #21633-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FMRP and MOV10 regulate Dicer1 expression and dendrite development.
Microtubule-associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in spinal muscular atrophy.
FMRP-absence-induced up-regulation of hypothalamic MAP1B expression decreases AgRP level linking with reduces in food intake and body weight.
Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.
MAP1B-LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules.
eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability.
GIT1 enhances neurite outgrowth by stimulating microtubule assembly.
Lannom MC, Nielsen J, Nawaz A, Shilikbay T, Ceman S
PloS one 2021;16(11):e0260005
PloS one 2021;16(11):e0260005
Microtubule-associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in spinal muscular atrophy.
Bora G, Hensel N, Rademacher S, Koyunoğlu D, Sunguroğlu M, Aksu-Mengeş E, Balcı-Hayta B, Claus P, Erdem-Yurter H
Human molecular genetics 2021 Feb 25;29(24):3935-3944
Human molecular genetics 2021 Feb 25;29(24):3935-3944
FMRP-absence-induced up-regulation of hypothalamic MAP1B expression decreases AgRP level linking with reduces in food intake and body weight.
Long JY, Jiang W, Xia HB, Fu JY, Lu P, Hu F, Feng WC, Sun WW, Gao MM, Yi YH, Long YS
Neurochemistry international 2020 Nov;140:104847
Neurochemistry international 2020 Nov;140:104847
Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.
Cui L, Zheng J, Zhao Q, Chen JR, Liu H, Peng G, Wu Y, Chen C, He Q, Shi H, Yin S, Friedman RA, Chen Y, Guan MX
JCI insight 2020 Dec 3;5(23)
JCI insight 2020 Dec 3;5(23)
MAP1B-LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules.
Arasaki K, Nagashima H, Kurosawa Y, Kimura H, Nishida N, Dohmae N, Yamamoto A, Yanagi S, Wakana Y, Inoue H, Tagaya M
EMBO reports 2018 Aug;19(8)
EMBO reports 2018 Aug;19(8)
eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Heise C, Taha E, Murru L, Ponzoni L, Cattaneo A, Guarnieri FC, Montani C, Mossa A, Vezzoli E, Ippolito G, Zapata J, Barrera I, Ryazanov AG, Cook J, Poe M, Stephen MR, Kopanitsa M, Benfante R, Rusconi F, Braida D, Francolini M, Proud CG, Valtorta F, Passafaro M, Sala M, Bachi A, Verpelli C, Rosenblum K, Sala C
Cerebral cortex (New York, N.Y. : 1991) 2017 Mar 1;27(3):2226-2248
Cerebral cortex (New York, N.Y. : 1991) 2017 Mar 1;27(3):2226-2248
Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability.
Wu J, He Z, Wang DL, Sun FL
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2980-2991
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2980-2991
GIT1 enhances neurite outgrowth by stimulating microtubule assembly.
Li YS, Qin LX, Liu J, Xia WL, Li JP, Shen HL, Gao WQ
Neural regeneration research 2016 Mar;11(3):427-34
Neural regeneration research 2016 Mar;11(3):427-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 21633-1-AP(MAP1B antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAP1B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MAP1B. This antibody recognizes human,mouse,rat antigen. The MAP1B antibody has been validated for the following applications: ELISA, WB, IHC analysis.