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- References [14]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10833-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10833-1-AP, RRID:AB_2098246
- Product name
- EPHX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EPHX2 antibody (Cat. #10833-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibiting Soluble Epoxide Hydrolase Suppresses NF-κB p65 Signaling and Reduces CXCL10 Expression as a Potential Therapeutic Target in Hashimoto's Thyroiditis.
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.
Santacruzamate A Alleviates Pain and Pain-Related Adverse Emotions through the Inhibition of Microglial Activation in the Anterior Cingulate Cortex.
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
The effect of acupuncture on lateral habenular nucleus and intestinal microflora in depression model rats.
L-theanine regulates the immune function of SD rats fed high-protein diets through the FABP5/IL-6/STAT3/PPARα pathway.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
Soluble epoxide hydrolase and TRPC3 channels jointly contribute to homocysteine-induced cardiac hypertrophy: Interrelation and regulation by C/EBPβ.
EPHX2 Inhibits Colon Cancer Progression by Promoting Fatty Acid Degradation.
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification.
Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma.
Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase.
Feng J, Xu X, Cai W, Yang X, Niu R, Han Z, Tian L
The Journal of clinical endocrinology and metabolism 2024 Sep 16;109(10):2579-2588
The Journal of clinical endocrinology and metabolism 2024 Sep 16;109(10):2579-2588
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.
Wang Y, Wang M, Su H, Song J, Ren M, Hu P, Liu G, Tong X
Free radical biology & medicine 2024 Feb 20;212:284-294
Free radical biology & medicine 2024 Feb 20;212:284-294
Santacruzamate A Alleviates Pain and Pain-Related Adverse Emotions through the Inhibition of Microglial Activation in the Anterior Cingulate Cortex.
Qin Y, Liu Q, Wang S, Wang Q, Du Y, Yao J, Chen Y, Yang Q, Wu Y, Liu S, Zhao M, Wei G, Yang L
ACS pharmacology & translational science 2024 Apr 12;7(4):1002-1012
ACS pharmacology & translational science 2024 Apr 12;7(4):1002-1012
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Zhang J, Luan ZL, Huo XK, Zhang M, Morisseau C, Sun CP, Hammock BD, Ma XC
International journal of biological sciences 2023;19(1):294-310
International journal of biological sciences 2023;19(1):294-310
The effect of acupuncture on lateral habenular nucleus and intestinal microflora in depression model rats.
Chen W, Chen Y, Aslam MS, Shen J, Tong T, Yan S, Cheng W, Huang Z, Li J, Liu S, Li J, Zeng J, Li M, You Z, Meng X
Behavioural brain research 2023 Oct 18;455:114627
Behavioural brain research 2023 Oct 18;455:114627
L-theanine regulates the immune function of SD rats fed high-protein diets through the FABP5/IL-6/STAT3/PPARα pathway.
Zhang Y, Song Y, Zhang J, Li L, He L, Bo J, Gong Z, Xiao W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114095
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114095
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC
ACS central science 2023 Mar 22;9(3):440-456
ACS central science 2023 Mar 22;9(3):440-456
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
Zhao C, Jiang X, Peng L, Zhang Y, Li H, Zhang Q, Wang Y, Yang F, Wu J, Wen Z, He Z, Shen J, Chen C, Wang DW
Journal of molecular and cellular cardiology 2023 Dec;185:13-25
Journal of molecular and cellular cardiology 2023 Dec;185:13-25
Soluble epoxide hydrolase and TRPC3 channels jointly contribute to homocysteine-induced cardiac hypertrophy: Interrelation and regulation by C/EBPβ.
Zhou Y, Wang XC, Wei JH, Xue HM, Sun WT, He GW, Yang Q
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166643
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166643
EPHX2 Inhibits Colon Cancer Progression by Promoting Fatty Acid Degradation.
Zhou Y, Li X, Guan A, Zhou H, Zhu Y, Wang R, Li R
Frontiers in oncology 2022;12:870721
Frontiers in oncology 2022;12:870721
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
Zhu X, Li K, Gao Y
Biochemical and biophysical research communications 2022 May 28;606:121-127
Biochemical and biophysical research communications 2022 May 28;606:121-127
An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification.
Lu S, Meng Z, Tan Y, Wu C, Huang Z, Huang J, Fu C, Stalin A, Guo S, Liu X, You L, Li X, Zhang J, Zhou W, Zhang X, Wang M, Wu J
BMC complementary medicine and therapies 2022 Mar 2;22(1):54
BMC complementary medicine and therapies 2022 Mar 2;22(1):54
Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma.
Zhan K, Bai Y, Liao S, Chen H, Kuang L, Luo Q, Lv L, Qiu L, Mei Z
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase.
Labitzke EM, Diani-Moore S, Rifkind AB
Archives of biochemistry and biophysics 2007 Dec 1;468(1):70-81
Archives of biochemistry and biophysics 2007 Dec 1;468(1):70-81
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10833-1-AP(EPHX2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EPHX2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EPHX2. This antibody recognizes human antigen. The EPHX2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
