PB9427

antibody from Boster Biological Technology
Targeting: HPSE HPA, HPSE1, HSE1
Provider product page for PB9427
Western blot

Antibody data

Product number
PB9427 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-Heparanase 1/HPSE Antibody Picoband™
Antibody type
Polyclonal
Description
Polyclonal antibody for HEPARANASE/HPSE detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. HEPARANASE/HPSE information: Molecular Weight: 61149 MW; Subcellular Localization: Lysosome membrane; Peripheral membrane protein. Secreted. Nucleus. Proheparanase is secreted via vesicles of the Golgi. Interacts with cell membrane heparan sulfate proteoglycans (HSPGs). Endocytosed and accumulates in endosomes. Transferred to lysosomes where it is proteolytically cleaved to produce the active enzyme. Under certain stimuli, transferred to the cell surface. Associates with lipid rafts. Colocalizes with SDC1 in endosomal/lysosomal vesicles. Accumulates in perinuclear lysosomal vesicles. Heparin retains proheparanase in the extracellular medium (By similarity); Tissue Specificity: Highly expressed in placenta and spleen and weakly expressed in lymph node, thymus, peripheral blood leukocytes, bone marrow, endothelial cells, fetal liver and tumor tissues. Also expressed in hair follicles, specifically in both Henle's and Huxley's layers of inner the root sheath (IRS) at anagen phase.
Reactivity
Human, Rat
Host
Rabbit
Vial size
100μg/vial
Concentration
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Handling
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
HPSE protein structure - PB9427 shown in red.