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- Antigen structure
- References [24]
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- Product number
- 19968-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19968-1-AP, RRID:AB_10697685
- Product name
- LHCGR antibody
- Antibody type
- Polyclonal
- Description
- LHCGR antibody (Cat. #19968-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dietary methionine supplementation during the estrous cycle improves follicular development and estrogen synthesis in rats.
Phoenixin-14 as a novel direct regulator of porcine luteal cell functions†.
miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4.
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells.
Effects of chronic dichlorodiphenyldichloroethylene exposure on testosterone secretion and steroidogenic pathway in the male gonad.
Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats.
miR-143-3p Promotes Ovarian Granulosa Cell Senescence and Inhibits Estradiol Synthesis by Targeting UBE2E3 and LHCGR.
Downregulation of LHCGR Attenuates COX-2 Expression and Induces Luteinized Unruptured Follicle Syndrome in Endometriosis.
Acute hypoxia induced dysregulation of clock-controlled ovary functions.
Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide-induced premature ovarian failure.
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway.
MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα.
Effects of increasing intake of soybean oil on synthesis of testosterone in Leydig cells.
Effect of luteinizing hormone concentration on transcriptome and subcellular organelle phenotype of ovarian granulosa cells.
La(2)O(3) Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Evaluation of carvacrol on pituitary and sexual hormones and their receptors in the testicle of male diabetic rats.
β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway.
Placental biology of Down syndrome in relation to increased gene dosage.
Amyloid Precursor Protein Overexpression in Down Syndrome Trophoblast Reduces Cell Invasiveness and Interferes with Syncytialization.
Gestational and lactational exposure to di-isobutyl phthalate via diet in maternal mice decreases testosterone levels in male offspring.
Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice.
The RNA-binding protein, ZFP36L2, influences ovulation and oocyte maturation.
Neonatal exposure to 17α-ethynyl estradiol affects ovarian gene expression and disrupts reproductive cycles in female rats.
Yang G, Li S, Cai S, Zhou J, Ye Q, Zhang S, Chen F, Wang F, Zeng X
Food & function 2024 Jan 22;15(2):704-715
Food & function 2024 Jan 22;15(2):704-715
Phoenixin-14 as a novel direct regulator of porcine luteal cell functions†.
Mlyczyńska E, Kurowska P, Wachowska D, Grzesiak M, Dupont J, Rak A
Biology of reproduction 2024 Jan 13;110(1):154-168
Biology of reproduction 2024 Jan 13;110(1):154-168
miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4.
Ju W, Zhao S, Wu H, Yu Y, Li Y, Liu D, Lian F, Xiang S
Reproductive biology and endocrinology : RB&E 2024 Feb 1;22(1):17
Reproductive biology and endocrinology : RB&E 2024 Feb 1;22(1):17
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Hu R, Huang Y, Geng Y, Liu Z, Li F, Zhang Z, Ma W, Song K, Dong H, Song Y, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117654
Journal of ethnopharmacology 2024 Apr 6;323:117654
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells.
Wang B, Gao M, Yao Y, Shen H, Li H, Sun J, Wang L, Zhang X
Reproductive biology and endocrinology : RB&E 2024 Apr 4;22(1):37
Reproductive biology and endocrinology : RB&E 2024 Apr 4;22(1):37
Effects of chronic dichlorodiphenyldichloroethylene exposure on testosterone secretion and steroidogenic pathway in the male gonad.
Molina EM, Kavazis AN, Mendonça MT, Akingbemi BT
Biology of reproduction 2023 Jul 11;109(1):65-72
Biology of reproduction 2023 Jul 11;109(1):65-72
Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats.
Wang H, Feng X, Wang T, Pan J, Zheng Z, Su Y, Weng H, Zhang L, Chen L, Zhou L, Zheng L
General and comparative endocrinology 2023 Jan 1;330:114138
General and comparative endocrinology 2023 Jan 1;330:114138
miR-143-3p Promotes Ovarian Granulosa Cell Senescence and Inhibits Estradiol Synthesis by Targeting UBE2E3 and LHCGR.
Deng J, Tang Y, Li L, Huang R, Wang Z, Ye T, Xiao Z, Hu M, Wei S, Wang Y, Yang Y, Huang Y
International journal of molecular sciences 2023 Aug 8;24(16)
International journal of molecular sciences 2023 Aug 8;24(16)
Downregulation of LHCGR Attenuates COX-2 Expression and Induces Luteinized Unruptured Follicle Syndrome in Endometriosis.
Geng T, Sun Y, Cheng L, Cao Y, Zhang M, Hong Z, Ma L, Zhang Y
Frontiers in endocrinology 2022;13:853563
Frontiers in endocrinology 2022;13:853563
Acute hypoxia induced dysregulation of clock-controlled ovary functions.
Ding M, Lu Y, Huang X, Xing C, Hou S, Wang D, Zhang Y, Wang W, Zhang C, Zhang M, Meng F, Liu K, Liu G, Zhao J, Song L
Frontiers in physiology 2022;13:1024038
Frontiers in physiology 2022;13:1024038
Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide-induced premature ovarian failure.
Zheng S, Ma M, Chen Y, Li M
Basic & clinical pharmacology & toxicology 2022 Feb;130(2):240-253
Basic & clinical pharmacology & toxicology 2022 Feb;130(2):240-253
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway.
Jin H, Yan M, Pan C, Liu Z, Sha X, Jiang C, Li L, Pan M, Li D, Han X, Ding J
Particle and fibre toxicology 2022 Feb 17;19(1):13
Particle and fibre toxicology 2022 Feb 17;19(1):13
MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα.
Wang YM, Wu Y, Zheng YF, Wang HY
Cell death & disease 2021 Oct 25;12(11):999
Cell death & disease 2021 Oct 25;12(11):999
Effects of increasing intake of soybean oil on synthesis of testosterone in Leydig cells.
Su Y, Tian Z, Qi X, Luo D, Liu L, Liu S, Zheng D, Wei F, He Z, Guan Q
Nutrition & metabolism 2021 May 26;18(1):53
Nutrition & metabolism 2021 May 26;18(1):53
Effect of luteinizing hormone concentration on transcriptome and subcellular organelle phenotype of ovarian granulosa cells.
Wan YT, Liu S, Zhao SK, Luo YY, Lv YS, Qu DN, Liu MH, Li Y
Journal of assisted reproduction and genetics 2021 Apr;38(4):809-824
Journal of assisted reproduction and genetics 2021 Apr;38(4):809-824
La(2)O(3) Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, An T, Chen Y, Zhang X
International journal of nanomedicine 2020;15:3415-3431
International journal of nanomedicine 2020;15:3415-3431
Evaluation of carvacrol on pituitary and sexual hormones and their receptors in the testicle of male diabetic rats.
Shoorei H, Khaki A, Shokoohi M, Khaki AA, Alihemmati A, Moghimian M, Abtahi-Eivary SH
Human & experimental toxicology 2020 Aug;39(8):1019-1030
Human & experimental toxicology 2020 Aug;39(8):1019-1030
β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway.
Wu W, Gao H, Li X, Peng S, Yu J, Liu N, Zhan G, Zhu Y, Wang K, Guo X
Cell cycle (Georgetown, Tex.) 2019 Jan;18(1):46-59
Cell cycle (Georgetown, Tex.) 2019 Jan;18(1):46-59
Placental biology of Down syndrome in relation to increased gene dosage.
Wong OGW, Ngan HYS, Cheung ANY
Hong Kong medical journal = Xianggang yi xue za zhi 2019 Aug;25 Suppl 5(4):33-35
Hong Kong medical journal = Xianggang yi xue za zhi 2019 Aug;25 Suppl 5(4):33-35
Amyloid Precursor Protein Overexpression in Down Syndrome Trophoblast Reduces Cell Invasiveness and Interferes with Syncytialization.
Wong OGW, Cheung CLY, Ip PPC, Ngan HYS, Cheung ANY
The American journal of pathology 2018 Oct;188(10):2307-2317
The American journal of pathology 2018 Oct;188(10):2307-2317
Gestational and lactational exposure to di-isobutyl phthalate via diet in maternal mice decreases testosterone levels in male offspring.
Wang X, Sheng N, Cui R, Zhang H, Wang J, Dai J
Chemosphere 2017 Apr;172:260-267
Chemosphere 2017 Apr;172:260-267
Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice.
Liu Y, Su X, Hao J, Chen M, Liu W, Liao X, Li G
International journal of molecular sciences 2016 Jan 13;17(1)
International journal of molecular sciences 2016 Jan 13;17(1)
The RNA-binding protein, ZFP36L2, influences ovulation and oocyte maturation.
Ball CB, Rodriguez KF, Stumpo DJ, Ribeiro-Neto F, Korach KS, Blackshear PJ, Birnbaumer L, Ramos SB
PloS one 2014;9(5):e97324
PloS one 2014;9(5):e97324
Neonatal exposure to 17α-ethynyl estradiol affects ovarian gene expression and disrupts reproductive cycles in female rats.
Nozawa K, Nagaoka K, Zhang H, Usuda K, Okazaki S, Taya K, Yoshida M, Watanabe G
Reproductive toxicology (Elmsford, N.Y.) 2014 Jul;46:77-84
Reproductive toxicology (Elmsford, N.Y.) 2014 Jul;46:77-84
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LHCGR antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human LHCGR. This antibody recognizes human,mouse,rat antigen. The LHCGR antibody has been validated for the following applications: ELISA, WB analysis.
