orb386092

antibody from Biorbyt
Targeting: LHCGR HHG, LCGR, LGR2, LHR, ULG5
Provider product page for orb386092
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb386092 - Provider product page
Provider
Biorbyt
Product name
hCG Receptor / LH Receptor Antibody
Antibody type
Monoclonal
Description
Recognizes a protein of 78-85kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
LHCGR/1415
Vial size
20 ug
Storage
Store the hCG Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
LHCGR protein structure - orb386092 shown in red.