UGT1A6

gene product
GNT1, HLUGP, UGT1F
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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112 antibodies from 24 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Santa Cruz Biotechnology
1 antibody
antibodies-online
48 antibodies
Biorbyt
11 antibodies
Novus Biologicals
4 antibodies
Aviva Systems Biology
3 antibodies
Invitrogen Antibodies
3 antibodies
OriGene
3 antibodies
Atlas Antibodies
1 antibody
GeneTex
1 antibody
Signalway Antibody LLC
1 antibody
LifeSpan BioSciences, Inc.
11 antibodies
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
St John's Laboratory
1 antibody
Abnova Corporation
4 antibodies
Creative Biolabs
4 antibodies
RabMAbs
3 antibodies
Creative Diagnostics
3 antibodies
MyBioSource
2 antibodies
Abgent
1 antibody
Sigma-Aldrich
2 antibodies
Abbexa
1 antibody
GenWay
1 antibody
United States Biological
1 antibody