Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 21632-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21632-1-AP, RRID:AB_11182931
- Product name
- KIF5B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIF5B antibody (Cat. #21632-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells.
Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability.
Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.
Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex.
Transport of c-MYC by Kinesin-1 for proteasomal degradation in the cytoplasm.
Kang Y, Yin S, Liu J, Jiang Y, Huang Z, Chen L, Shao L
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
Chen XQ, Das U, Park G, Mobley WC
Alzheimer's research & therapy 2021 Mar 10;13(1):59
Alzheimer's research & therapy 2021 Mar 10;13(1):59
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, Zhu L, Wu JY
EMBO reports 2021 Jul 5;22(7):e52006
EMBO reports 2021 Jul 5;22(7):e52006
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
Hou W, Kang W, Li Y, Shan Y, Wang S, Liu F
Virulence 2021 Dec;12(1):615-629
Virulence 2021 Dec;12(1):615-629
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
Wang Q, Tian J, Chen H, Du H, Guo L
Neurobiology of disease 2019 Jul;127:410-418
Neurobiology of disease 2019 Jul;127:410-418
Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells.
Franchini DM, Lanvin O, Tosolini M, Patras de Campaigno E, Cammas A, Péricart S, Scarlata CM, Lebras M, Rossi C, Ligat L, Pont F, Arimondo PB, Laurent C, Ayyoub M, Despas F, Lapeyre-Mestre M, Millevoi S, Fournié JJ
Cell reports 2019 Jan 2;26(1):94-107.e7
Cell reports 2019 Jan 2;26(1):94-107.e7
Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability.
Adam F, Kauskot A, Kurowska M, Goudin N, Munoz I, Bordet JC, Huang JD, Bryckaert M, Fischer A, Borgel D, de Saint Basile G, Christophe OD, Ménasché G
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1037-1051
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1037-1051
Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.
Pesaresi M, Giatti S, Spezzano R, Romano S, Diviccaro S, Borsello T, Mitro N, Caruso D, Garcia-Segura LM, Melcangi RC
Biology of sex differences 2018 Jan 19;9(1):6
Biology of sex differences 2018 Jan 19;9(1):6
Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex.
Munoz I, Danelli L, Claver J, Goudin N, Kurowska M, Madera-Salcedo IK, Huang JD, Fischer A, González-Espinosa C, de Saint Basile G, Blank U, Ménasché G
The Journal of cell biology 2016 Oct 24;215(2):203-216
The Journal of cell biology 2016 Oct 24;215(2):203-216
Transport of c-MYC by Kinesin-1 for proteasomal degradation in the cytoplasm.
Lee CM
Biochimica et biophysica acta 2014 Sep;1843(9):2027-36
Biochimica et biophysica acta 2014 Sep;1843(9):2027-36
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIF5B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human KIF5B. This antibody recognizes human,mouse,rat antigen. The KIF5B antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21632-1-AP(KIF5B antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21632-1-AP(KIF5B antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue