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- Antibody Data
- Antigen structure
- References [24]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15585-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15585-1-AP, RRID:AB_10697653
- Product name
- SFPQ antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SFPQ antibody (Cat. #15585-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA.
Multiple Oligo assisted RNA Pulldown via Hybridization followed by Mass Spectrometry (MORPH-MS) for exploring the RNA-Protein interactions.
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
The splicing factor proline and glutamine rich promotes the growth of osteosarcoma via the c-Myc signaling pathway.
Decreased LONP1 expression contributes to DNA damage and meiotic defects in oocytes.
K235 acetylation couples with PSPC1 to regulate the m(6)A demethylation activity of ALKBH5 and tumorigenesis.
SFPQ and Its Isoform as Potential Biomarker for Non-Small-Cell Lung Cancer.
LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation.
Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention.
Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
The tumor-suppressive effects of alpha-ketoglutarate-dependent dioxygenase FTO via N6-methyladenosine RNA methylation on bladder cancer patients.
LncRNA nuclear-enriched abundant transcript 1 shuttled by prostate cancer cells-secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR-205-5p/runt-related transcription factor 2/splicing factor proline- and glutamine-rich/polypyrimidine tract-binding protein 2 axis.
Splicing Regulator p54(nrb) /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.
AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma.
Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer.
The lncRNA Neat1 promotes activation of inflammasomes in macrophages.
Characterization of telomeric repeat-containing RNA (TERRA) localization and protein interactions in primordial germ cells of the mouse†.
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Synergistic upregulation of NONO and PSPC1 regulates Sertoli cell response to MEHP via modulation of ALDH1A1 signaling.
New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.
Proteins implicated in the increase of adhesivity induced by suberoylanilide hydroxamic acid in leukemic cells.
Liu Y, Jiang H, Hu K, Zou H, Zhang W, Liu J, Jian X
PloS one 2024;19(4):e0298947
PloS one 2024;19(4):e0298947
Multiple Oligo assisted RNA Pulldown via Hybridization followed by Mass Spectrometry (MORPH-MS) for exploring the RNA-Protein interactions.
Pant P, Kumarswamy R
RNA biology 2024 Jan;21(1):1-9
RNA biology 2024 Jan;21(1):1-9
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
Wang X, Fan X, Zhang J, Wang F, Chen J, Wen Y, Wang L, Li T, Li H, Gu H, Zhang Y, Yuan S
Cell reports 2024 Feb 27;43(2):113769
Cell reports 2024 Feb 27;43(2):113769
The splicing factor proline and glutamine rich promotes the growth of osteosarcoma via the c-Myc signaling pathway.
Mao L, Jiang P, Lei X, Zhang B, Zhong X, Yin Z, Wang Y, Li D, Zhang Y, Zheng Q
American journal of cancer research 2023;13(6):2488-2503
American journal of cancer research 2023;13(6):2488-2503
Decreased LONP1 expression contributes to DNA damage and meiotic defects in oocytes.
Liu C, Xu M, Guan Y, Li L, Liu W, Guo B, Sheng X, Zhang Y, Zhou J, Zhen X, Yan G, Sun H, Ding L
Molecular reproduction and development 2023 Jun;90(6):358-368
Molecular reproduction and development 2023 Jun;90(6):358-368
K235 acetylation couples with PSPC1 to regulate the m(6)A demethylation activity of ALKBH5 and tumorigenesis.
Zhang XL, Chen XH, Xu B, Chen M, Zhu S, Meng N, Wang JZ, Zhu H, Chen D, Liu JB, Yan GR
Nature communications 2023 Jun 27;14(1):3815
Nature communications 2023 Jun 27;14(1):3815
SFPQ and Its Isoform as Potential Biomarker for Non-Small-Cell Lung Cancer.
Yang L, Gilbertsen A, Jacobson B, Pham J, Fujioka N, Henke CA, Kratzke RA
International journal of molecular sciences 2023 Aug 6;24(15)
International journal of molecular sciences 2023 Aug 6;24(15)
LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation.
Yang Y, Li M, Ma Y, Ye W, Si Y, Zheng X, Liu H, Cheng L, Zhang L, Zhang H, Zhang X, Lei Y, Shen L, Zhang F, Ma H
Frontiers in microbiology 2022;13:849020
Frontiers in microbiology 2022;13:849020
Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention.
Wang X, Han M, Wang S, Sun Y, Zhao W, Xue Z, Liang X, Huang B, Li G, Chen A, Li X, Wang J
Theranostics 2022;12(12):5451-5469
Theranostics 2022;12(12):5451-5469
Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.
Zhang S, Huang W, Ren L, Ju X, Gong M, Rao J, Sun L, Li P, Ding Q, Wang J, Zhang QC
Cell research 2022 Jan;32(1):9-23
Cell research 2022 Jan;32(1):9-23
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
Sun S, Gao T, Pang B, Su X, Guo C, Zhang R, Pang Q
Cell death & disease 2022 Jan 21;13(1):73
Cell death & disease 2022 Jan 21;13(1):73
MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.
Miao H, Wu F, Li Y, Qin C, Zhao Y, Xie M, Dai H, Yao H, Cai H, Wang Q, Song X, Li L
Science advances 2022 Dec 23;8(51):eabq7289
Science advances 2022 Dec 23;8(51):eabq7289
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, Chen Z, Yin X, Sun C, Mao Y, Zhou F, Shao Y, Liu Q, Xu J, Cheng L, Yu D, Li P, Yi P, He J, Geng G, Guo Q, Si Y, Zhao H, Li H, Banes GL, Liu H, Nakamura Y, Kurita R, Huang Y, Wang X, Wang F, Fang G, Engel JD, Shi L, Zhang YE, Yu J
Developmental cell 2021 Feb 22;56(4):478-493.e11
Developmental cell 2021 Feb 22;56(4):478-493.e11
The tumor-suppressive effects of alpha-ketoglutarate-dependent dioxygenase FTO via N6-methyladenosine RNA methylation on bladder cancer patients.
Yi W, Yu Y, Li Y, Yang J, Gao S, Xu L
Bioengineered 2021 Dec;12(1):5323-5333
Bioengineered 2021 Dec;12(1):5323-5333
LncRNA nuclear-enriched abundant transcript 1 shuttled by prostate cancer cells-secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR-205-5p/runt-related transcription factor 2/splicing factor proline- and glutamine-rich/polypyrimidine tract-binding protein 2 axis.
Mo C, Huang B, Zhuang J, Jiang S, Guo S, Mao X
Clinical and translational medicine 2021 Aug;11(8):e493
Clinical and translational medicine 2021 Aug;11(8):e493
Splicing Regulator p54(nrb) /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.
Hu Z, Dong L, Li S, Li Z, Qiao Y, Li Y, Ding J, Chen Z, Wu Y, Wang Z, Huang S, Gao Q, Zhao Y, He X
Hepatology (Baltimore, Md.) 2020 Aug;72(2):548-568
Hepatology (Baltimore, Md.) 2020 Aug;72(2):548-568
AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma.
He SW, Xu C, Li YQ, Li YQ, Zhao Y, Zhang PP, Lei Y, Liang YL, Li JY, Li Q, Chen Y, Huang SY, Ma J, Liu N
Oncogene 2020 Aug;39(34):5616-5632
Oncogene 2020 Aug;39(34):5616-5632
Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer.
Xu S, Zhan M, Jiang C, He M, Yang L, Shen H, Huang S, Huang X, Lin R, Shi Y, Liu Q, Chen W, Mohan M, Wang J
Nature communications 2019 Dec 2;10(1):5492
Nature communications 2019 Dec 2;10(1):5492
The lncRNA Neat1 promotes activation of inflammasomes in macrophages.
Zhang P, Cao L, Zhou R, Yang X, Wu M
Nature communications 2019 Apr 2;10(1):1495
Nature communications 2019 Apr 2;10(1):1495
Characterization of telomeric repeat-containing RNA (TERRA) localization and protein interactions in primordial germ cells of the mouse†.
Brieño-Enríquez MA, Moak SL, Abud-Flores A, Cohen PE
Biology of reproduction 2019 Apr 1;100(4):950-962
Biology of reproduction 2019 Apr 1;100(4):950-962
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F
Journal of virology 2017 May 1;91(9)
Journal of virology 2017 May 1;91(9)
Synergistic upregulation of NONO and PSPC1 regulates Sertoli cell response to MEHP via modulation of ALDH1A1 signaling.
Dong BW, Jin XH, Yan CY, Yang T, Cai GQ, Lu J
FEBS letters 2017 Mar;591(6):914-923
FEBS letters 2017 Mar;591(6):914-923
New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.
Huang R, Yu M, Li CY, Zhan YQ, Xu WX, Xu F, Ge CH, Li W, Yang XM
Proteomics. Clinical applications 2012 Oct;6(9-10):467-75
Proteomics. Clinical applications 2012 Oct;6(9-10):467-75
Proteins implicated in the increase of adhesivity induced by suberoylanilide hydroxamic acid in leukemic cells.
Grebeňová D, Röselová P, Pluskalová M, Halada P, Rösel D, Suttnar J, Brodská B, Otevřelová P, Kuželová K
Journal of proteomics 2012 Dec 21;77:406-22
Journal of proteomics 2012 Dec 21;77:406-22
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15585-1-AP(SFPQ antibody) at dilution of 1:700
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15585-1-AP(SFPQ antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SFPQ antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SFPQ. This antibody recognizes human, mouse, rat antigen. The SFPQ antibody has been validated for the following applications: ELISA, WB, IHC analysis.
