Antibody data
- Antibody Data
- Antigen structure
- References [29]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14552-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14552-1-AP, RRID:AB_2250751
- Product name
- MT1-MMP antibody
- Antibody type
- Polyclonal
- Description
- MT1-MMP antibody (Cat. #14552-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Basement membrane-related MMP14 predicts poor prognosis and response to immunotherapy in bladder cancer.
FOLR1-stabilized β-catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK-3β pathway.
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury.
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Heat Shock Proteins 70 Regulate Cell Motility and Invadopodia-Associated Proteins Expression in Oral Squamous Cell Carcinoma.
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
PLOD2 Is a Prognostic Marker in Glioblastoma That Modulates the Immune Microenvironment and Tumor Progression.
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
LOXL1-AS1 communicating with TIAR modulates vasculogenic mimicry in glioma via regulation of the miR-374b-5p/MMP14 axis.
Dual VEGF/PDGF knockdown suppresses vasculogenic mimicry formation in choroidal melanoma cells via the Wnt5a/β-catenin/AKT signaling pathway.
METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway.
SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
Transition of podosomes into zipper-like structures in macrophage-derived multinucleated giant cells.
Upregulation of SPOCK2 inhibits the invasion and migration of prostate cancer cells by regulating the MT1-MMP/MMP2 pathway.
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
NAB 2-Expressing Cancer-Associated Fibroblast Promotes HNSCC Progression.
Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis.
MT1-MMP downregulation via the PI3K/Akt signaling pathway is required for the mechanical stretching-inhibited invasion of bone-marrow-derived mesenchymal stem cells.
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.
MMP-14 aggravates onset of severe preeclampsia by mediating soluble endoglin release.
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis.
Zhang X, Hong B, Li H, Zhao J, Li M, Wei D, Wang Y, Zhang N
BMC cancer 2024 Jun 19;24(1):746
BMC cancer 2024 Jun 19;24(1):746
FOLR1-stabilized β-catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK-3β pathway.
Tuo H, Li X, Du H, Li M, Xu C, Yu Z, Zhao H
Molecular carcinogenesis 2024 Jan;63(1):34-44
Molecular carcinogenesis 2024 Jan;63(1):34-44
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury.
Wang C, Xu Y, Xu M, Sun C, Zhang X, Tao X, Song T
Journal of neuroinflammation 2024 Feb 22;21(1):57
Journal of neuroinflammation 2024 Feb 22;21(1):57
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Li B, Chen J, Wu Y, Luo H, Ke Y
International journal of biological sciences 2022;18(13):5123-5135
International journal of biological sciences 2022;18(13):5123-5135
Heat Shock Proteins 70 Regulate Cell Motility and Invadopodia-Associated Proteins Expression in Oral Squamous Cell Carcinoma.
Ding LX, Zhang J, Yang SS, Wu J, Su T, Wang WM
Frontiers in endocrinology 2022;13:890218
Frontiers in endocrinology 2022;13:890218
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Guo D, Zhang X, Cui H, Yu D, Zhang H, Shi X, Pang C, Li J, Guo W, Zhang S
Frontiers in oncology 2022;12:821484
Frontiers in oncology 2022;12:821484
PLOD2 Is a Prognostic Marker in Glioblastoma That Modulates the Immune Microenvironment and Tumor Progression.
Kreße N, Schröder H, Stein KP, Wilkens L, Mawrin C, Sandalcioglu IE, Dumitru CA
International journal of molecular sciences 2022 May 27;23(11)
International journal of molecular sciences 2022 May 27;23(11)
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Ferrand N, Fert A, Morichon R, Radosevic-Robin N, Zaoui M, Sabbah M
Cancers 2022 Mar 14;14(6)
Cancers 2022 Mar 14;14(6)
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
Yao N, Zhou J, Song J, Jiang Y, Zhang J
Neoplasma 2022 Jul;69(4):764-775
Neoplasma 2022 Jul;69(4):764-775
LOXL1-AS1 communicating with TIAR modulates vasculogenic mimicry in glioma via regulation of the miR-374b-5p/MMP14 axis.
Yi B, Li H, Cai H, Lou X, Yu M, Li Z
Journal of cellular and molecular medicine 2022 Jan;26(2):475-490
Journal of cellular and molecular medicine 2022 Jan;26(2):475-490
Dual VEGF/PDGF knockdown suppresses vasculogenic mimicry formation in choroidal melanoma cells via the Wnt5a/β-catenin/AKT signaling pathway.
Yuan Y, Geng B, Xu X, Zhao H, Bai J, Dou Z, Jia S, Yu X, Luo W
Acta histochemica 2022 Jan;124(1):151842
Acta histochemica 2022 Jan;124(1):151842
METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
Jiang L, Liu X, Hu X, Gao L, Zeng H, Wang X, Huang Y, Zhu W, Wang J, Wen J, Meng X, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
Lin B, Liu J, Zhang Y, Wu Y, Chen S, Bai Y, Liu Q, Qin X
BMC genomics 2021 Nov 24;22(1):852
BMC genomics 2021 Nov 24;22(1):852
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
Ogoyama M, Ohkuchi A, Takahashi H, Zhao D, Matsubara S, Takizawa T
International journal of molecular sciences 2021 Jan 27;22(3)
International journal of molecular sciences 2021 Jan 27;22(3)
GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway.
Liu Y, Wang D, Lei M, Gao J, Cui Y, Jin X, Yu Q, Jiang Y, Guo Y, Liu Y, Cai L, Chen X
Aging 2021 Feb 11;13(4):5858-5874
Aging 2021 Feb 11;13(4):5858-5874
SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
Ren F, Wang D, Wang Y, Chen P, Guo C
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1391-1399
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1391-1399
Transition of podosomes into zipper-like structures in macrophage-derived multinucleated giant cells.
Balabiyev A, Podolnikova NP, Mursalimov A, Lowry D, Newbern JM, Roberson RW, Ugarova TP
Molecular biology of the cell 2020 Aug 15;31(18):2002-2020
Molecular biology of the cell 2020 Aug 15;31(18):2002-2020
Upregulation of SPOCK2 inhibits the invasion and migration of prostate cancer cells by regulating the MT1-MMP/MMP2 pathway.
Liu G, Ren F, Song Y
PeerJ 2019;7:e7163
PeerJ 2019;7:e7163
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, Jia S
BioMed research international 2019;2019:3909102
BioMed research international 2019;2019:3909102
SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
Ren F, Wang D, Wang Y, Chen P, Guo C
Reproductive sciences (Thousand Oaks, Calif.) 2019 Mar 4;:1933719119834341
Reproductive sciences (Thousand Oaks, Calif.) 2019 Mar 4;:1933719119834341
NAB 2-Expressing Cancer-Associated Fibroblast Promotes HNSCC Progression.
Choi SY, Oh SY, Kang SH, Kang SM, Kim J, Lee HJ, Kwon TG, Kim JW, Hong SH
Cancers 2019 Mar 19;11(3)
Cancers 2019 Mar 19;11(3)
Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis.
Wang D, Zheng J, Liu X, Xue Y, Liu L, Ma J, He Q, Li Z, Cai H, Liu Y
Molecular therapy. Nucleic acids 2019 Mar 1;14:465-482
Molecular therapy. Nucleic acids 2019 Mar 1;14:465-482
MT1-MMP downregulation via the PI3K/Akt signaling pathway is required for the mechanical stretching-inhibited invasion of bone-marrow-derived mesenchymal stem cells.
Fu X, Halim A, Tian B, Luo Q, Song G
Journal of cellular physiology 2019 Aug;234(8):14133-14144
Journal of cellular physiology 2019 Aug;234(8):14133-14144
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, Song E, Song Y
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Chemical research in toxicology 2018 Sep 17;31(9):954-963
MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.
Duan Y, Dong Y, Dang R, Hu Z, Yang Y, Hu Y, Cheng J
Cell biology international 2018 Nov;42(11):1564-1574
Cell biology international 2018 Nov;42(11):1564-1574
MMP-14 aggravates onset of severe preeclampsia by mediating soluble endoglin release.
Zhang XH, Zhang HY, Lu S, Jiang LL, Wu J, Yang YL, Zhang SA
European review for medical and pharmacological sciences 2018 Mar;22(5):1209-1215
European review for medical and pharmacological sciences 2018 Mar;22(5):1209-1215
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Guo J, Cai H, Liu X, Zheng J, Liu Y, Gong W, Chen J, Xi Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis.
Li Y, Wu Z, Yuan J, Sun L, Lin L, Huang N, Bin J, Liao Y, Liao W
Cancer letters 2017 Jun 1;395:31-44
Cancer letters 2017 Jun 1;395:31-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MMP14 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MMP14. This antibody recognizes human, mouse, rat, zebrafish antigen. The MMP14 antibody has been validated for the following applications: ELISA, WB analysis.