Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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- Product number
- 13892-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- GREM2 antibody
- Antibody type
- Polyclonal
- Description
- GREM2 antibody (Cat. #13892-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mesenchymal Stem Cells Mediated Suppression of GREM2 Inhibits Renal Epithelial-Mesenchymal Transition and Attenuates the Progression of Diabetic Kidney Disease.
Overexpression of miR-671-3p alleviates postmenopausal osteoporosis by targeting GREM2 to activate BMP2/SMAD signaling pathway.
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE(-/-) mice.
SGLT2 inhibitor empagliflozin downregulates miRNA-34a-5p and targets GREM2 to inactivate hepatic stellate cells and ameliorate non-alcoholic fatty liver disease-associated fibrosis.
Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2.
Genetic factors derived from the MRL/MpJ mouse function to maintain the integrity of spermatogenesis after heat exposure.
The onset of heat-induced testicular calcification in mice: involvement of the telomeric locus on chromosome 1.
Ko MS, Yun JY, Kim S, Kim MO, Go SH, Jin HJ, Koh EH
International journal of stem cells 2025 May 30;18(2):158-172
International journal of stem cells 2025 May 30;18(2):158-172
Overexpression of miR-671-3p alleviates postmenopausal osteoporosis by targeting GREM2 to activate BMP2/SMAD signaling pathway.
Liang Y, Gu C, Wang P, Gu C, Ma H, Ren S
Hereditas 2025 Jun 11;162(1):102
Hereditas 2025 Jun 11;162(1):102
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE(-/-) mice.
Brückner A, Brandtner A, Rieck S, Matthey M, Geisen C, Fels B, Stei M, Kusche-Vihrog K, Fleischmann BK, Wenzel D
Angiogenesis 2024 Nov;27(4):719-738
Angiogenesis 2024 Nov;27(4):719-738
SGLT2 inhibitor empagliflozin downregulates miRNA-34a-5p and targets GREM2 to inactivate hepatic stellate cells and ameliorate non-alcoholic fatty liver disease-associated fibrosis.
Shen Y, Cheng L, Xu M, Wang W, Wan Z, Xiong H, Guo W, Cai M, Xu F
Metabolism: clinical and experimental 2023 Sep;146:155657
Metabolism: clinical and experimental 2023 Sep;146:155657
Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2.
Bylund JB, Trinh LT, Awgulewitsch CP, Paik DT, Jetter C, Jha R, Zhang J, Nolan K, Xu C, Thompson TB, Kamp TJ, Hatzopoulos AK
Stem cells and development 2017 May 1;26(9):678-693
Stem cells and development 2017 May 1;26(9):678-693
Genetic factors derived from the MRL/MpJ mouse function to maintain the integrity of spermatogenesis after heat exposure.
Chihara M, Nakamura T, Otsuka-Kanazawa S, Ichii O, Elewa YH, Kon Y
Andrology 2015 Sep;3(5):991-9
Andrology 2015 Sep;3(5):991-9
The onset of heat-induced testicular calcification in mice: involvement of the telomeric locus on chromosome 1.
Chihara M, Nakamura T, Sakakibara N, Otsuka S, Ichii O, Kon Y
The American journal of pathology 2014 Sep;184(9):2480-92
The American journal of pathology 2014 Sep;184(9):2480-92
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 13892-1-AP(GREM2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GREM2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GREM2. This antibody recognizes human,mouse,rat antigen. The GREM2 antibody has been validated for the following applications: ELISA, IHC analysis.