BS60971
GREM2 antibody from Bioworld Technology, Inc
CKTSF1B2, DAND3, FLJ21195, Prdc
Antibody data
- Antibody Data
- Knockdown Reagents [0]
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60971
- Provider
- Bioworld Technology, Inc
- Product name
- GREM2 polyclonal antibody
- Provider product page
- Bioworld Technology, Inc - BS60971
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human GREM2.
- Description
- The gremlin protein family contains antagonists of bone morphogenetic protein (BMP) signaling that are expressed in the neural crest. All family members are secreted proteins that act as BMP antagonists in embryonic explants and are expressed in the proximal airway epithelium of the lung during embryonic development. Gremlin-1 is required for early limb outgrowth and patterning in the FGF4-SHH feedback loop, while gremlin-2 binds and blocks the activity of BMP-2 and BMP-4. The dorsaling factor gremlin belongs to a novel gene family that includes the head-inducing factor Cerberus and the tumor suppressor DAN. Additionally, secreted gremlin relays the sonic hedgehog signal from the polarizing region to the apical ectodermal ridge.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
| Provider | Type | Product Number |
|---|---|---|
| - No reagents - | ||
