BS60971

GREM2 antibody from Bioworld Technology, Inc
CKTSF1B2, DAND3, FLJ21195, Prdc

Antibody data

Product number
BS60971
Provider
Bioworld Technology, Inc
Product name
GREM2 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS60971
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human GREM2.
Description
The gremlin protein family contains antagonists of bone morphogenetic protein (BMP) signaling that are expressed in the neural crest. All family members are secreted proteins that act as BMP antagonists in embryonic explants and are expressed in the proximal airway epithelium of the lung during embryonic development. Gremlin-1 is required for early limb outgrowth and patterning in the FGF4-SHH feedback loop, while gremlin-2 binds and blocks the activity of BMP-2 and BMP-4. The dorsaling factor gremlin belongs to a novel gene family that includes the head-inducing factor Cerberus and the tumor suppressor DAN. Additionally, secreted gremlin relays the sonic hedgehog signal from the polarizing region to the apical ectodermal ridge.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -