RA0513

antibody from Oursmab

Targeting: MSTN GDF8

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0513

Provider

Oursmab

Product name

Trevogrumab (Biosimilar Reference Antibody) (MSTN)

Antibody type

Monoclonal

Description

Trevogrumab (REGN-1033) is a humanized IgG4 kappa monoclonal antibody targeting growth/differentiation factor 8 (GDF8, also known as myostatin), a negative regulator of skeletal muscle growth. It binds to and neutralizes myostatin, blocking its interaction with the activin type IIB receptor (ActRIIB) to promote muscle hypertrophy and strength. It is being developed for the treatment of sarcopenia, muscle-wasting disorders, and certain neuromuscular conditions.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Trevogrumab (Biosimilar Reference Antibody) (MSTN)-RA0513-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Trevogrumab (Biosimilar Reference Antibody) (MSTN)-RA0513 in a linear range of 15.63¨C125 ng/mL.