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- Antibody Data
- Antigen structure
- References [7]
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- Western blot [1]
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- Product number
- 13927-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13927-1-AP, RRID:AB_2111647
- Product name
- GNAQ antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GNAQ antibody (Cat. #13927-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Disruption of the interaction between mutationally activated Gα(q) and Gβγ attenuates aberrant signaling.
Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890.
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways.
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Aumiller JL, Wedegaertner PB
The Journal of biological chemistry 2023 Feb;299(2):102880
The Journal of biological chemistry 2023 Feb;299(2):102880
Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890.
Randolph CE, Dwyer MB, Aumiller JL, Dixon AJ, Inoue A, Osei-Owusu P, Wedegaertner PB
The Journal of biological chemistry 2022 Nov;298(11):102538
The Journal of biological chemistry 2022 Nov;298(11):102538
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Li Y, Yang J, Zhang Q, Xu S, Sun W, Ge S, Xu X, Jager MJ, Jia R, Zhang J, Fan X
Oncogene 2022 Jul;41(27):3539-3553
Oncogene 2022 Jul;41(27):3539-3553
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
Sasai M, Ma JS, Okamoto M, Nishino K, Nagaoka H, Takashima E, Pradipta A, Lee Y, Kosako H, Suh PG, Yamamoto M
The Journal of experimental medicine 2021 Jul 5;218(7)
The Journal of experimental medicine 2021 Jul 5;218(7)
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP
eLife 2018 Feb 2;7
eLife 2018 Feb 2;7
G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways.
Wang Y, Xiao H, Wu H, Yao C, He H, Wang C, Li W
Oncology reports 2017 Apr;37(4):1998-2006
Oncology reports 2017 Apr;37(4):1998-2006
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Chen H, Xu L, Yin L, Xu Y, Han X, Qi Y, Zhao Y, Liu K, Peng J
Proteomics 2014 Jan;14(1):51-73
Proteomics 2014 Jan;14(1):51-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GNAQ antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GNAQ. This antibody recognizes human, mouse antigen. The GNAQ antibody has been validated for the following applications: ELISA, WB analysis.
