Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350412 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350412, RRID:AB_10784421
- Product name
- anti-Potassium Channel, Subfamily K, Member 4 (KCNK4) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the c-terminal region of mouse KCNK4 (TRAAK) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and rat.
- Reactivity
- Human, Mouse, Rat
- Host
- Sheep
- Epitope
- C-Term
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Cloning of two transcripts, HKT4.1a and HKT4.1b, from the human two-pore K+ channel gene KCNK4. Chromosomal localization, tissue distribution and functional expression.
Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali.
Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel.
Inhalational anesthetics activate two-pore-domain background K+ channels.
A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids.
Ozaita A, Vega-Saenz de Miera E
Brain research. Molecular brain research 2002 Jun 15;102(1-2):18-27
Brain research. Molecular brain research 2002 Jun 15;102(1-2):18-27
Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali.
Kim Y, Bang H, Gnatenco C, Kim D
Pflugers Archiv : European journal of physiology 2001 Apr;442(1):64-72
Pflugers Archiv : European journal of physiology 2001 Apr;442(1):64-72
Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel.
Lesage F, Maingret F, Lazdunski M
FEBS letters 2000 Apr 14;471(2-3):137-40
FEBS letters 2000 Apr 14;471(2-3):137-40
Inhalational anesthetics activate two-pore-domain background K+ channels.
Patel AJ, Honoré E, Lesage F, Fink M, Romey G, Lazdunski M
Nature neuroscience 1999 May;2(5):422-6
Nature neuroscience 1999 May;2(5):422-6
A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids.
Fink M, Lesage F, Duprat F, Heurteaux C, Reyes R, Fosset M, Lazdunski M
The EMBO journal 1998 Jun 15;17(12):3297-308
The EMBO journal 1998 Jun 15;17(12):3297-308
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