DPABH-07319

POLR3G antibody from Creative Diagnostics
C31, RPC32, RPC7
Western blot
Recommended by provider
ELISA
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
DPABH-07319
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPABH-07319, RRID:AB_2510074
Product name
Rabbit Anti-Human POLR3G Polyclonal Antibody
Provider product page
Creative Diagnostics - DPABH-07319
Antibody type
Polyclonal
Description
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Concentration
Lot specific
Storage
Store at -20°C, and avoid repeat freeze-thaw cycles.