Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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- Product number
- ABIN2849692 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 210-239
- Antibody clone number
- RB7463
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Lipoxin A4 methyl ester alleviates vascular cognition impairment by regulating the expression of proteins related to autophagy and ER stress in the rat hippocampus.
Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma.
Curcumin-loaded γ-cyclodextrin liposomal nanoparticles as delivery vehicles for osteosarcoma.
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.
Degrade or die: a dual function for autophagy in the plant immune response.
Autophagy: dual roles in life and death?
Autophagy in metazoans: cell survival in the land of plenty.
Eating oneself and uninvited guests: autophagy-related pathways in cellular defense.
Autophagy in health and disease: a double-edged sword.
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.
Jia Y, Jin W, Xiao Y, Dong Y, Wang T, Fan M, Xu J, Meng N, Li L, Lv P
Cellular & molecular biology letters 2015 Sep;20(3):475-87
Cellular & molecular biology letters 2015 Sep;20(3):475-87
Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma.
Liu H, He Z, von Rütte T, Yousefi S, Hunger RE, Simon HU
Science translational medicine 2013 Sep 11;5(202):202ra123
Science translational medicine 2013 Sep 11;5(202):202ra123
Curcumin-loaded γ-cyclodextrin liposomal nanoparticles as delivery vehicles for osteosarcoma.
Dhule SS, Penfornis P, Frazier T, Walker R, Feldman J, Tan G, He J, Alb A, John V, Pochampally R
Nanomedicine : nanotechnology, biology, and medicine 2012 May;8(4):440-51
Nanomedicine : nanotechnology, biology, and medicine 2012 May;8(4):440-51
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.
Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D, Denmark T
The Journal of biological chemistry 2009 Aug 7;284(32):21412-24
The Journal of biological chemistry 2009 Aug 7;284(32):21412-24
Degrade or die: a dual function for autophagy in the plant immune response.
Greenberg JT
Developmental cell 2005 Jun;8(6):799-801
Developmental cell 2005 Jun;8(6):799-801
Autophagy: dual roles in life and death?
Baehrecke EH
Nature reviews. Molecular cell biology 2005 Jun;6(6):505-10
Nature reviews. Molecular cell biology 2005 Jun;6(6):505-10
Autophagy in metazoans: cell survival in the land of plenty.
Lum JJ, DeBerardinis RJ, Thompson CB
Nature reviews. Molecular cell biology 2005 Jun;6(6):439-48
Nature reviews. Molecular cell biology 2005 Jun;6(6):439-48
Eating oneself and uninvited guests: autophagy-related pathways in cellular defense.
Levine B
Cell 2005 Jan 28;120(2):159-62
Cell 2005 Jan 28;120(2):159-62
Autophagy in health and disease: a double-edged sword.
Shintani T, Klionsky DJ
Science (New York, N.Y.) 2004 Nov 5;306(5698):990-5
Science (New York, N.Y.) 2004 Nov 5;306(5698):990-5
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.
Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B
Journal of virology 1998 Nov;72(11):8586-96
Journal of virology 1998 Nov;72(11):8586-96
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Supportive validation
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- Submitted by
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- WB
- Submitted by
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC