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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
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- Product number
- ABIN497977 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Beclin 1, Autophagy Related (BECN1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Beclin-1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human Beclin-1.
- Description
- Immunoaffinity Chromatography
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.
Autophagy as a cell death and tumor suppressor mechanism.
Induction of autophagy and inhibition of tumorigenesis by beclin 1.
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.
Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae.
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B
Cell 2005 Sep 23;122(6):927-39
Cell 2005 Sep 23;122(6):927-39
Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
Induction of autophagy and inhibition of tumorigenesis by beclin 1.
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B
Nature 1999 Dec 9;402(6762):672-6
Nature 1999 Dec 9;402(6762):672-6
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.
Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B
Journal of virology 1998 Nov;72(11):8586-96
Journal of virology 1998 Nov;72(11):8586-96
Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae.
Kametaka S, Okano T, Ohsumi M, Ohsumi Y
The Journal of biological chemistry 1998 Aug 28;273(35):22284-91
The Journal of biological chemistry 1998 Aug 28;273(35):22284-91
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5
Carcinogenesis 1993 Dec;14(12):2501-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP20057PU-N Beclin-1 antibody staining of A431 cell lysate by Western Blotting at (A) 0.5, (B) 1 and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP20057PU-N Beclin-1 antibody staining of A431 cells by Immunofluorescence at 2 ?g/ml.
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP20057PU-N Beclin-1 antibody staining of A431 cells by Immunocytochemistry at 1 ?g/ml.
