Antibody data
- Antibody Data
- Antigen structure
- References [71]
- Comments [0]
- Validations [0]
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- Product number
- 66665-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Beclin 1 antibody
- Antibody type
- Monoclonal
- Description
- Beclin 1 antibody (Cat. #66665-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C10C4
- Vial size
- 20ul, 150ul
Submitted references Autophagy in Multiple Sclerosis: Phagocytosis and Autophagy of Oligodendrocyte Precursor Cells.
Potassium ion channel Kir2.1 negatively regulates protective responses to Mycobacterium bovis BCG.
Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia.
Modulation of autophagy affected tumorigenesis induced by the envelope glycoprotein of JSRV.
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Induction of Peroxiredoxin 1 by Hypoxia Promotes Cellular Autophagy and Cell Proliferation in Oral Leukoplakia via HIF-1α/BNIP3 Pathway.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma.
Palmatine treats urticaria by reducing inflammation and increasing autophagy.
Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis.
EGCG identified as an autophagy inducer for rosacea therapy.
Glucosamine-loaded injectable hydrogel promotes autophagy and inhibits apoptosis after cartilage injury.
Intermittent fasting combined with exercise training reduces body mass and alleviates hypothalamic disorders induced by high-fat diet intake.
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy.
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Plasma metabonomic study on the effect of Para‑hydroxybenzaldehyde intervention in a rat model of transient focal cerebral ischemia.
Crosstalk between autophagy inhibitor and salidroside-induced apoptosis: A novel strategy for autophagy-based treatment of hepatocellular cancer.
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination.
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator.
A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis.
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Protective Effect and Mechanism of Kuntai Capsule on Angiotensin II -Induced Hypertension in Ovariectomized Rats.
DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells.
SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia.
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Exosomes Derived From M2 Microglia Cells Attenuates Neuronal Impairment and Mitochondrial Dysfunction in Alzheimer's Disease Through the PINK1/Parkin Pathway.
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Moxidectin induces autophagy arrest in colorectal cancer.
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1.
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
1α,25(OH)(2)D(3)(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis.
Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway.
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway.
Modulatory effects of curcumin on Singapore grouper iridovirus infection-associated apoptosis and autophagy in vitro.
Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage.
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis.
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis.
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway.
Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing.
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway.
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues.
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy.
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Co-delivery of doxorubicin and shRNA of Beclin1 by folate receptor targeted pullulan-based multifunctional nanomicelles for combinational cancer therapy.
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Wang JQ, Li Q, He JY, Zhou F, Huang ZH, Wang LB, Zhang Y, Li X
Molecular neurobiology 2024 Sep;61(9):6920-6933
Molecular neurobiology 2024 Sep;61(9):6920-6933
Potassium ion channel Kir2.1 negatively regulates protective responses to Mycobacterium bovis BCG.
Sinha V, Singh A, Singh A, Saraswati SSK, Rana AK, Kalra K, Natarajan K
Journal of leukocyte biology 2024 Sep 2;116(3):644-656
Journal of leukocyte biology 2024 Sep 2;116(3):644-656
Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia.
Li Z, Zhang F, Huang L, Deng J, Pan Y, Xu T, Liu J, Gao N, Duan R, Shao C, Wu C, Wang M, Lu L
Neurochemical research 2024 Mar;49(3):670-683
Neurochemical research 2024 Mar;49(3):670-683
Modulation of autophagy affected tumorigenesis induced by the envelope glycoprotein of JSRV.
Zhang L, Yang H, Duan X, Li H, Xu S, Chen H, Wang J, Wang Y, Liu S
Virology 2024 Jun;594:110059
Virology 2024 Jun;594:110059
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Zhao Y, Ding ZG, Yan YJ, Yang R, Qi MM, Pan SK, Xie JL, Sun YH, Xiang J
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Induction of Peroxiredoxin 1 by Hypoxia Promotes Cellular Autophagy and Cell Proliferation in Oral Leukoplakia via HIF-1α/BNIP3 Pathway.
Li J, Li W, Li L, Wang W, Zhang M, Tang X
Journal of molecular histology 2024 Aug;55(4):403-413
Journal of molecular histology 2024 Aug;55(4):403-413
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma.
Pan Z, Li SJ, Guo H, Li ZH, Fei X, Chang SM, Yang QC, Cheng DD
International journal of biological sciences 2023;19(2):537-551
International journal of biological sciences 2023;19(2):537-551
Palmatine treats urticaria by reducing inflammation and increasing autophagy.
Xiao T, Yu X, Yang L, Duan X
Frontiers in immunology 2023;14:1268467
Frontiers in immunology 2023;14:1268467
Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis.
Guo J, Yin J, Liu P, Zhang X, Wei J, Wang M, Xiao Y, Zhen Y, Lin Y, Li J
Frontiers in pharmacology 2023;14:1219486
Frontiers in pharmacology 2023;14:1219486
EGCG identified as an autophagy inducer for rosacea therapy.
Zhou L, Zhong Y, Wang Y, Deng Z, Huang Y, Wang Q, Xie H, Zhang Y, Li J
Frontiers in pharmacology 2023;14:1092473
Frontiers in pharmacology 2023;14:1092473
Glucosamine-loaded injectable hydrogel promotes autophagy and inhibits apoptosis after cartilage injury.
Chang Y, Wang Y, Liu J, Chen X, Ma X, Hu Y, Tian H, Wang X, Mu C
Heliyon 2023 Sep;9(9):e19879
Heliyon 2023 Sep;9(9):e19879
Intermittent fasting combined with exercise training reduces body mass and alleviates hypothalamic disorders induced by high-fat diet intake.
Oliveira LDC, Morais GP, de Oliveira FP, Mata MM, Veras ASC, da Rocha AL, Elias LLK, Teixeira GR, de Moraes C, Cintra DE, Ropelle ER, de Moura LP, Pauli JR, de Freitas EC, Rorato R, da Silva ASR
The Journal of nutritional biochemistry 2023 Sep;119:109372
The Journal of nutritional biochemistry 2023 Sep;119:109372
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Zhou Q, Fang G, Pang Y, Wang X
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy.
Castillo Bautista CM, Eismann K, Gentzel M, Pelucchi S, Mertens J, Walters HE, Yun MH, Sterneckert J
Cells 2023 Sep 11;12(18)
Cells 2023 Sep 11;12(18)
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Yang Q, Zou Y, Wei X, Ye P, Wu Y, Ai H, Zhang Z, Tan J, Zhou J, Yang Y, Dai Q, Dou C, Luo F
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Hu H, Wang Y, Dong Y, Wang L, Chen Y, Zhou Y, Sun L
Molecular biology reports 2023 Nov;50(11):8985-8993
Molecular biology reports 2023 Nov;50(11):8985-8993
Plasma metabonomic study on the effect of Para‑hydroxybenzaldehyde intervention in a rat model of transient focal cerebral ischemia.
Yu X, Luo Y, Yang L, Duan X
Molecular medicine reports 2023 Nov;28(5)
Molecular medicine reports 2023 Nov;28(5)
Crosstalk between autophagy inhibitor and salidroside-induced apoptosis: A novel strategy for autophagy-based treatment of hepatocellular cancer.
Jiang B, Cui Y, Ma X, Zhang Y, Feng X, Yang T, Feng L, Guo W, Li Y, Wang T, Guo H, Li H, Duan Y, Su H
International immunopharmacology 2023 Nov;124(Pt B):111040
International immunopharmacology 2023 Nov;124(Pt B):111040
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination.
Ma Q, Yu J, Liu L, Ma X, Zhang J, Zhang J, Wang X, Deng G, Wu X
Cell death discovery 2023 Nov 28;9(1):427
Cell death discovery 2023 Nov 28;9(1):427
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
Liu J, Zhu Q, Pan Y, Hao S, Wang Z, Cui C, Li J, Huang Y, Xia L, Xu T, Cheng J, Shen J, Xia Y
Molecular human reproduction 2023 Nov 1;29(11)
Molecular human reproduction 2023 Nov 1;29(11)
Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator.
Liao Q, Su L, Pang L, Li J, Li H, Li J, Liu Y, Zhang J
Journal of nanobiotechnology 2023 May 26;21(1):169
Journal of nanobiotechnology 2023 May 26;21(1):169
A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis.
Chen J, Feng D, Lu Y, Zhang Y, Jiang H, Yuan M, Xu Y, Zou J, Zhu Y, Zhang J, Ge C, Wang Y
Cancers 2023 Mar 5;15(5)
Cancers 2023 Mar 5;15(5)
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Xing J, Qiao G, Luo X, Liu S, Chen S, Ye G, Zhang C, Yi J
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468
Protective Effect and Mechanism of Kuntai Capsule on Angiotensin II -Induced Hypertension in Ovariectomized Rats.
Ge XF, Li SS, Liu YH, Lu MQ, Su HN, Yang X, Sun XW
Chinese journal of integrative medicine 2023 Jun;29(6):526-533
Chinese journal of integrative medicine 2023 Jun;29(6):526-533
DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
Yu W, Ma L, Li X
Oncology reports 2023 Feb;49(2)
Oncology reports 2023 Feb;49(2)
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Hu Y, Jiang H, Xu Y, Chen G, Fan R, Zhou Y, Liu Y, Yao Y, Liu R, Chen W, Zhang K, Chen X, Wang R, Qiu Z
Cell death discovery 2023 Feb 14;9(1):63
Cell death discovery 2023 Feb 14;9(1):63
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Xu Y, Wang Y, Xiao H, Li Y
Journal of periodontal research 2023 Dec;58(6):1248-1260
Journal of periodontal research 2023 Dec;58(6):1248-1260
Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells.
Wang D, Han S, Lv G, Hu Y, Zhuo W, Zeng Z, Tang J, Huang Y, Wang F, Wang J, Zhao Y, Zhao G
Gastroenterology 2023 Dec;165(6):1488-1504.e20
Gastroenterology 2023 Dec;165(6):1488-1504.e20
SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia.
Yang Q, Li C, Chen Q
Frontiers in cardiovascular medicine 2022;9:789331
Frontiers in cardiovascular medicine 2022;9:789331
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Meng X, Li M, Qiao M, Li X, Yang J, Hu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Exosomes Derived From M2 Microglia Cells Attenuates Neuronal Impairment and Mitochondrial Dysfunction in Alzheimer's Disease Through the PINK1/Parkin Pathway.
Li N, Shu J, Yang X, Wei W, Yan A
Frontiers in cellular neuroscience 2022;16:874102
Frontiers in cellular neuroscience 2022;16:874102
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Qian Y, Yang Y, Qing W, Li C, Kong M, Kang Z, Zuo Y, Wu J, Yu M, Yang Z
Frontiers in microbiology 2022;13:962766
Frontiers in microbiology 2022;13:962766
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Luo L, Gong J, Wang Z, Liu Y, Cao J, Qin J, Zuo R, Zhang H, Wang S, Zhao P, Yang D, Zhang M, Wang Y, Zhang J, Zhou Y, Li C, Ni B, Tian Z, Liu M
Bioactive materials 2022 Sep;15:29-43
Bioactive materials 2022 Sep;15:29-43
Moxidectin induces autophagy arrest in colorectal cancer.
Mao Y, Xie H, Shu D, Cheng L, Lan J, Pan K
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Zhao Y, Lin J, Li J, Bwalya C, Xu Y, Niu Y, Zhang Y, Wu J, Xu Y, Chen J, Ye S, Lin L
International journal of molecular sciences 2022 Oct 18;23(20)
International journal of molecular sciences 2022 Oct 18;23(20)
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells.
Deng L, Zhao M, Cui Y, Xia Q, Jiang L, Yin H, Zhao L
Drug and chemical toxicology 2022 Nov;45(6):2601-2612
Drug and chemical toxicology 2022 Nov;45(6):2601-2612
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1.
Rong Y, Fan J, Ji C, Wang Z, Ge X, Wang J, Ye W, Yin G, Cai W, Liu W
Cell death and differentiation 2022 Jun;29(6):1164-1175
Cell death and differentiation 2022 Jun;29(6):1164-1175
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278
Stem cell research & therapy 2022 Jun 28;13(1):278
1α,25(OH)(2)D(3)(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis.
Li Z, Xu B, Sun Y, Zhou L, Tao Y, Hou W, Bao J, Liu J, Fan W
Bioengineered 2022 Jan;13(1):357-369
Bioengineered 2022 Jan;13(1):357-369
Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway.
Liu P, Wu A, Li H, Zhang J, Ni J, Quan Z, Qing H
International journal of molecular sciences 2022 Jan 20;23(3)
International journal of molecular sciences 2022 Jan 20;23(3)
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Wu J, Lin T, Gao Y, Li X, Yang C, Zhang K, Wang C, Zhou X
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway.
Yang L, Liang B, Li J, Zhang X, Chen H, Sun J, Zhang Z
Cellular signalling 2022 Feb;90:110206
Cellular signalling 2022 Feb;90:110206
Modulatory effects of curcumin on Singapore grouper iridovirus infection-associated apoptosis and autophagy in vitro.
Wang Y, Xu S, Han C, Huang Y, Wei J, Wei S, Qin Q
Fish & shellfish immunology 2022 Dec;131:84-94
Fish & shellfish immunology 2022 Dec;131:84-94
Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage.
Pinto AP, da Rocha AL, Marafon BB, Nogueira JE, Branco LGS, Pauli JR, de Moura LP, Cintra DE, Ropelle ER, da Silva ASR
Clinical and experimental pharmacology & physiology 2022 Aug;49(8):893-902
Clinical and experimental pharmacology & physiology 2022 Aug;49(8):893-902
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Yuan T, Wang J, Shi C, Wang Y, Xia B, Xu W, Yang H, Yang Y, Ye MT, Khalid S, Liang Y, Tian C, You MJ, Wang Y
Hematological oncology 2022 Apr;40(2):249-257
Hematological oncology 2022 Apr;40(2):249-257
HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis.
Tan Y, Huang Y, Mei R, Mao F, Yang D, Liu J, Xu W, Qian H, Yan Y
Cell death & disease 2022 Apr 8;13(4):319
Cell death & disease 2022 Apr 8;13(4):319
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
Luo Q, Li X, Gan G, Yang M, Chen X, Chen F
Frontiers in cell and developmental biology 2021;9:764263
Frontiers in cell and developmental biology 2021;9:764263
Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
Yang R, Wen J, Yang T, Dai C, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis.
Sun Z, Qu J, Xia X, Pan Y, Liu X, Liang H, Dou H, Hou Y
International journal of biological sciences 2021;17(2):460-474
International journal of biological sciences 2021;17(2):460-474
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway.
Zhou W, Shi Y, Wang H, Yu C, Zhu H, Wu A
Frontiers in pharmacology 2021;12:713491
Frontiers in pharmacology 2021;12:713491
Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing.
Qiang L, Yang S, Cui YH, He YY
Autophagy 2021 Sep;17(9):2128-2143
Autophagy 2021 Sep;17(9):2128-2143
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
Chang XM, Xiao F, Pan Q, Wang XX, Guo LX
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Han J, Wang L, Lv H, Liu J, Dong Y, Shi L, Ji Q
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, Chen Y, Liu A, Wu Q, Sun L, Xu F, Hu F, Chen L, Luo X, Feng Y, Huang S, Hu J, Wang G
Nature communications 2021 Jun 15;12(1):3651
Nature communications 2021 Jun 15;12(1):3651
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Yang RZ, Zheng HL, Xu WN, Zheng XF, Li B, Jiang LS, Jiang SD
Aging 2021 Feb 1;13(3):4647-4662
Aging 2021 Feb 1;13(3):4647-4662
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Deng Y, Chen QS, Huang WF, Dai JW, Wu ZJ
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Apr 10;216:112181
Ecotoxicology and environmental safety 2021 Apr 10;216:112181
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway.
Feng J, Li C, Xu R, Li Y, Hou Q, Feng R, Wang S, Zhang L, Li C
Oxidative medicine and cellular longevity 2020;2020:9762390
Oxidative medicine and cellular longevity 2020;2020:9762390
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
Feng TY, Li Q, Ren F, Xi HM, Lv DL, Li Y, Hu JH
Oxidative medicine and cellular longevity 2020;2020:5954635
Oxidative medicine and cellular longevity 2020;2020:5954635
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Zhang Y, Huang N, Xu J, Zheng W, Cui X
Drug design, development and therapy 2020;14:4749-4763
Drug design, development and therapy 2020;14:4749-4763
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Xu Z, Feng J, Li Y, Guan D, Chen H, Zhai X, Zhang L, Li C, Li C
Chemico-biological interactions 2020 Sep 1;328:109196
Chemico-biological interactions 2020 Sep 1;328:109196
Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues.
da Rocha AL, Pinto AP, Morais GP, Marafon BB, Rovina RL, Veras ASC, Teixeira GR, Pauli JR, de Moura LP, Cintra DE, Ropelle ER, Rivas DA, da Silva ASR
International journal of molecular sciences 2020 Nov 10;21(22)
International journal of molecular sciences 2020 Nov 10;21(22)
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy.
Sun P, Nie K, Zhu Y, Liu Y, Wu P, Liu Z, Du S, Fan H, Chen CH, Zhang R, Wang P, Cheng G
Nature communications 2020 Jan 14;11(1):260
Nature communications 2020 Jan 14;11(1):260
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
Pinto AP, Vieira TS, Marafon BB, Batitucci G, Cabrera EMB, da Rocha AL, Kohama EB, Rodrigues KCC, de Moura LP, Pauli JR, Cintra DE, Ropelle ER, de Freitas EC, da Silva ASR
Nutrients 2020 Feb 28;12(3)
Nutrients 2020 Feb 28;12(3)
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Xu G, Wang X, Yu H, Wang C, Liu Y, Zhao R, Zhang G
Human & experimental toxicology 2019 Jul;38(7):794-802
Human & experimental toxicology 2019 Jul;38(7):794-802
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Wang N, Yang B, Muhetaer G, Wang S, Zheng Y, Lu J, Li M, Zhang F, Situ H, Lin Y, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Co-delivery of doxorubicin and shRNA of Beclin1 by folate receptor targeted pullulan-based multifunctional nanomicelles for combinational cancer therapy.
Chen L, Qian M, Zhang L, Xia J, Bao Y, Wang J, Guo L, Li Y
RSC advances 2018 May 14;8(32):17710-17722
RSC advances 2018 May 14;8(32):17710-17722
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Wu L, Wang C, Li J, Li S, Feng J, Liu T, Xu S, Wang W, Lu X, Chen K, Xia Y, Fan X, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1137-1146
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1137-1146
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