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- References [9]
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- Product number
- ABIN387797 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Beclin 1, Autophagy Related (BECN1) (full length) antibody
- Antibody type
- Monoclonal
- Description
- Ascites
- Reactivity
- Human
- Host
- Mouse
- Epitope
- full length
- Isotype
- IgG
- Antibody clone number
- 15CT26
- Vial size
- 0.1 mL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Echovirus 7 entry into polarized caco-2 intestinal epithelial cells involves core components of the autophagy machinery.
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle.
Activation of autophagy in mesenchymal stem cells provides tumor stromal support.
Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7.
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors.
Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease.
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells.
Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis.
Kim C, Bergelson JM
Journal of virology 2014 Jan;88(1):434-43
Journal of virology 2014 Jan;88(1):434-43
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle.
Starr T, Child R, Wehrly TD, Hansen B, Hwang S, López-Otin C, Virgin HW, Celli J
Cell host & microbe 2012 Jan 19;11(1):33-45
Cell host & microbe 2012 Jan 19;11(1):33-45
Activation of autophagy in mesenchymal stem cells provides tumor stromal support.
Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, Rowan BG, Kelekar A, Krause DS, Pochampally RR
Carcinogenesis 2011 Jul;32(7):964-72
Carcinogenesis 2011 Jul;32(7):964-72
Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7.
Metzger S, Saukko M, Van Che H, Tong L, Puder Y, Riess O, Nguyen HP
Human genetics 2010 Oct;128(4):453-9
Human genetics 2010 Oct;128(4):453-9
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors.
Li Z, Chen B, Wu Y, Jin F, Xia Y, Liu X
BMC cancer 2010 Mar 16;10:98
BMC cancer 2010 Mar 16;10:98
Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease.
Ma JF, Huang Y, Chen SD, Halliday G
Neuropathology and applied neurobiology 2010 Jun;36(4):312-9
Neuropathology and applied neurobiology 2010 Jun;36(4):312-9
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
Jaeger PA, Pickford F, Sun CH, Lucin KM, Masliah E, Wyss-Coray T
PloS one 2010 Jun 15;5(6):e11102
PloS one 2010 Jun 15;5(6):e11102
Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells.
Sun Y, Liu JH, Jin L, Lin SM, Yang Y, Sui YX, Shi H
Cancer letters 2010 Aug 28;294(2):204-10
Cancer letters 2010 Aug 28;294(2):204-10
Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis.
Niu TK, Cheng Y, Ren X, Yang JM
FEBS letters 2010 Aug 20;584(16):3519-24
FEBS letters 2010 Aug 20;584(16):3519-24
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
