ABIN1001879

antibody from antibodies-online

Targeting: BECN1 ATG6, VPS30

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1001879

Provider

antibodies-online

Product name

anti-Beclin 1, Autophagy Related (BECN1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Rabbit polyclol Beclin-1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Beclin-1 (Genbank accession No. AAH10276).

Description

Affinity chromatography purified via peptide column.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

Autophagy as a cell death and tumor suppressor mechanism.

Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906

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Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.

Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B
Journal of virology 1998 Nov;72(11):8586-96

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Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae.

Kametaka S, Okano T, Ohsumi M, Ohsumi Y
The Journal of biological chemistry 1998 Aug 28;273(35):22284-91

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Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.

Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5