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Immunohistochemistry
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Other assay [1]
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- Product number
- MA1-21194 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Laminin alpha-1 Monoclonal Antibody (4C7)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- This antibody reacts with the terminal globular domain of the A chain. It does not cross react with laminin from mouse or rat. The staining with this antibody is sensitive to fixation of paraffin tissues and use of proteolytic enzymatic treatment. Recommended positive control: skin tissue.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4C7
- Vial size
- 500 µL
- Concentration
- Conc. Not Determined
- Storage
- 4° C, do not freeze
Submitted references Controlling the 3D architecture of Self-Lifting Auto-generated Tissue Equivalents (SLATEs) for optimized corneal graft composition and stability.
Nasal seromucinous hamartoma (microglandular adenosis of the nose): a morphological and molecular study of five cases.
Trypanosoma cruzi induces tissue disorganization and destruction of chorionic villi in an ex vivo infection model of human placenta.
Melatonin protects against epirubicin-induced cardiotoxicity.
Investigation of the effects of heparin and low molecular weight heparin on E-cadherin and laminin expression in rat pregnancy by immunohistochemistry.
Gouveia RM, González-Andrades E, Cardona JC, González-Gallardo C, Ionescu AM, Garzon I, Alaminos M, González-Andrades M, Connon CJ
Biomaterials 2017 Mar;121:205-219
Biomaterials 2017 Mar;121:205-219
Nasal seromucinous hamartoma (microglandular adenosis of the nose): a morphological and molecular study of five cases.
Ambrosini-Spaltro A, Morandi L, Spagnolo DV, Cavazza A, Brisigotti M, Damiani S, Jain S, Eusebi V
Virchows Archiv : an international journal of pathology 2010 Dec;457(6):727-34
Virchows Archiv : an international journal of pathology 2010 Dec;457(6):727-34
Trypanosoma cruzi induces tissue disorganization and destruction of chorionic villi in an ex vivo infection model of human placenta.
Duaso J, Rojo G, Cabrera G, Galanti N, Bosco C, Maya JD, Morello A, Kemmerling U
Placenta 2010 Aug;31(8):705-11
Placenta 2010 Aug;31(8):705-11
Melatonin protects against epirubicin-induced cardiotoxicity.
Guven A, Yavuz O, Cam M, Ercan F, Bukan N, Comunoglu C
Acta histochemica 2007;109(1):52-60
Acta histochemica 2007;109(1):52-60
Investigation of the effects of heparin and low molecular weight heparin on E-cadherin and laminin expression in rat pregnancy by immunohistochemistry.
Erden O, Imir A, Guvenal T, Muslehiddinoglu A, Arici S, Cetin M, Cetin A
Human reproduction (Oxford, England) 2006 Nov;21(11):3014-8
Human reproduction (Oxford, England) 2006 Nov;21(11):3014-8
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Fig. 9 Corneal stromal SLATEs as substrates for human corneal epithelial cell growth. Epithelial cells isolated from human corneas were grown on A- and R-SLATEs for 2 weeks with Cnt-7 medium, followed by an additional 2 weeks period with SHEM in air-lifting conditions, and then imaged by immunofluorescence confocal microscopy. Expression of A) CK3 and collagen-IV, B) CK15 and ABCG2, C) DeltaNp63 and beta1-integrins, D) YAP and ZO-1, or E) laminin and collagen-VII was analyzed by tridimensional reconstruction of a 300 x 300 mum area ( large panels ) and corresponding cross-section views of projected composites ( small panels ). Cell nuclei were identified by DAPI staining. F) Signal specificity was evaluated using secondary antibody-only controls. Fig. 9
