Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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- Product number
- BAF306 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-7R alpha/CD127 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-7 R alpha in Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele.
CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections.
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults.
Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.
IL-7 restores lymphocyte functions in septic patients.
Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells.
Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients.
Al-Mossawi H, Yager N, Taylor CA, Lau E, Danielli S, de Wit J, Gilchrist J, Nassiri I, Mahe EA, Lee W, Rizvi L, Makino S, Cheeseman J, Neville M, Knight JC, Bowness P, Fairfax BP
Nature communications 2019 Oct 8;10(1):4575
Nature communications 2019 Oct 8;10(1):4575
CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections.
Judge CJ, Kostadinova L, Sherman KE, Butt AA, Falck-Ytter Y, Funderburg NT, Landay AL, Lederman MM, Sieg SF, Sandberg JK, Anthony DD
Journal of leukocyte biology 2017 Jul;102(1):171-184
Journal of leukocyte biology 2017 Jul;102(1):171-184
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults.
Poiret T, Rane L, Remberger M, Omazic B, Gustafsson-Jernberg A, Vudattu NK, Ahmed R, Ernberg I, Winiarski J, Magalhaes I, Ringden O, Maeurer M
BMC immunology 2014 Jun 19;15:25
BMC immunology 2014 Jun 19;15:25
Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.
Kreft KL, Verbraak E, Wierenga-Wolf AF, van Meurs M, Oostra BA, Laman JD, Hintzen RQ
Genes and immunity 2012 Oct;13(7):587-92
Genes and immunity 2012 Oct;13(7):587-92
IL-7 restores lymphocyte functions in septic patients.
Venet F, Foray AP, Villars-Méchin A, Malcus C, Poitevin-Later F, Lepape A, Monneret G
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov 15;189(10):5073-81
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov 15;189(10):5073-81
Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells.
Hoe E, McKay FC, Schibeci SD, Gandhi K, Heard RN, Stewart GJ, Booth DR
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2512-7
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2512-7
Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients.
Rose T, Lambotte O, Pallier C, Delfraissy JF, Colle JH
Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 15;182(12):7389-97
Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 15;182(12):7389-97
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