Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- BAF306 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-7R alpha/CD127 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-7 R alpha in Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections.
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults.
Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.
IL-7 restores lymphocyte functions in septic patients.
Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells.
Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients.
Judge CJ, Kostadinova L, Sherman KE, Butt AA, Falck-Ytter Y, Funderburg NT, Landay AL, Lederman MM, Sieg SF, Sandberg JK, Anthony DD
Journal of leukocyte biology 2017 Jul;102(1):171-184
Journal of leukocyte biology 2017 Jul;102(1):171-184
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults.
Poiret T, Rane L, Remberger M, Omazic B, Gustafsson-Jernberg A, Vudattu NK, Ahmed R, Ernberg I, Winiarski J, Magalhaes I, Ringden O, Maeurer M
BMC immunology 2014 Jun 19;15:25
BMC immunology 2014 Jun 19;15:25
Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.
Kreft KL, Verbraak E, Wierenga-Wolf AF, van Meurs M, Oostra BA, Laman JD, Hintzen RQ
Genes and immunity 2012 Oct;13(7):587-92
Genes and immunity 2012 Oct;13(7):587-92
IL-7 restores lymphocyte functions in septic patients.
Venet F, Foray AP, Villars-Méchin A, Malcus C, Poitevin-Later F, Lepape A, Monneret G
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov 15;189(10):5073-81
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov 15;189(10):5073-81
Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells.
Hoe E, McKay FC, Schibeci SD, Gandhi K, Heard RN, Stewart GJ, Booth DR
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2512-7
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2512-7
Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients.
Rose T, Lambotte O, Pallier C, Delfraissy JF, Colle JH
Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 15;182(12):7389-97
Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 15;182(12):7389-97
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