Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19492-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19492-1-AP, RRID:AB_10638445
- Product name
- ADCY3 antibody
- Antibody type
- Polyclonal
- Description
- ADCY3 antibody (Cat. #19492-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cerebral furin deficiency causes hydrocephalus in mice.
Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway.
Anti-miR-141-3p maintains homeostasis between autophagy and apoptosis by targeting Yy1 in the fetal lumbosacral defecation center of rats.
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Preferential Expression of Ca(2+)-Stimulable Adenylyl Cyclase III in the Supraventricular Area, including Arrhythmogenic Pulmonary Vein of the Rat Heart.
Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.
Phenotypic characterization of Cdkl5-knockdown neurons establishes elongated cilia as a functional assay for CDKL5 Deficiency Disorder.
Targeting the HDAC6-Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity.
Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function.
Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
A Cell-Based Assay Optimized for High-Content Cilia Imaging with Primary Rat Hippocampal Neurons.
Aromatherapy: Activating olfactory calcium-sensing receptors impairs renal hemodynamics via sympathetic nerve-mediated vasoconstriction.
Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease.
Xie S, Xie X, Tang J, Luo B, Chen J, Wen Q, Zhou J, Chen G
Genes & diseases 2024 May;11(3):101009
Genes & diseases 2024 May;11(3):101009
Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway.
Qi R, Liang Y, Yu J, Chen B, Jiang J, Wu X, Lu W, Li Z
Reproductive biology and endocrinology : RB&E 2024 Mar 20;22(1):31
Reproductive biology and endocrinology : RB&E 2024 Mar 20;22(1):31
Anti-miR-141-3p maintains homeostasis between autophagy and apoptosis by targeting Yy1 in the fetal lumbosacral defecation center of rats.
Li Y, Liu P, Yao Y, Wang W, Jia H, Bai Y, Yuan Z, Yang Z
Molecular therapy. Nucleic acids 2024 Jun 11;35(2):102163
Molecular therapy. Nucleic acids 2024 Jun 11;35(2):102163
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Luo S, Li Y, Li S, Jiang R, Deng F, Liu G, Zhang J
Frontiers in physiology 2022;13:856427
Frontiers in physiology 2022;13:856427
Preferential Expression of Ca(2+)-Stimulable Adenylyl Cyclase III in the Supraventricular Area, including Arrhythmogenic Pulmonary Vein of the Rat Heart.
Okamoto Y, Aung NY, Tanaka M, Takeda Y, Takagi D, Igarashi W, Ishii K, Yamakawa M, Ono K
Biomolecules 2022 May 20;12(5)
Biomolecules 2022 May 20;12(5)
Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.
Long HP, Liu J, Xu PS, Xu KP, Li J, Tan GS
Phytochemistry 2022 Mar;195:113073
Phytochemistry 2022 Mar;195:113073
Phenotypic characterization of Cdkl5-knockdown neurons establishes elongated cilia as a functional assay for CDKL5 Deficiency Disorder.
Di Nardo A, Rühmkorf A, Award P, Brennecke A, Fagiolini M, Sahin M
Neuroscience research 2022 Mar;176:73-78
Neuroscience research 2022 Mar;176:73-78
Targeting the HDAC6-Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity.
Ran J, Zhang Y, Zhang S, Li H, Zhang L, Li Q, Qin J, Li D, Sun L, Xie S, Zhang X, Liu L, Liu M, Zhou J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jul;9(21):e2105365
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jul;9(21):e2105365
Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function.
Gailey CD, Wang EJ, Jin L, Ahmadi S, Brautigan DL, Li X, Xu W, Scott MM, Fu Z
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Feb;250(2):263-273
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Feb;250(2):263-273
Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
Di Nardo A, Lenoël I, Winden KD, Rühmkorf A, Modi ME, Barrett L, Ercan-Herbst E, Venugopal P, Behne R, Lopes CAM, Kleiman RJ, Bettencourt-Dias M, Sahin M
Cell reports 2020 Jun 23;31(12):107780
Cell reports 2020 Jun 23;31(12):107780
A Cell-Based Assay Optimized for High-Content Cilia Imaging with Primary Rat Hippocampal Neurons.
Di Nardo A, Vasquez S, Sahin M
STAR protocols 2020 Dec 18;1(3):100189
STAR protocols 2020 Dec 18;1(3):100189
Aromatherapy: Activating olfactory calcium-sensing receptors impairs renal hemodynamics via sympathetic nerve-mediated vasoconstriction.
Lee SP, Wu WY, Hsiao JK, Zhou JH, Chang HH, Chien CT
Acta physiologica (Oxford, England) 2019 Jan;225(1):e13157
Acta physiologica (Oxford, England) 2019 Jan;225(1):e13157
Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease.
Canterini S, Dragotto J, Dardis A, Zampieri S, De Stefano ME, Mangia F, Erickson RP, Fiorenza MT
Human molecular genetics 2017 Jun 15;26(12):2277-2289
Human molecular genetics 2017 Jun 15;26(12):2277-2289
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 19492-1-AP(ADCY3 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ADCY3 antibody 19492-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ADCY3 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ADCY3. This antibody recognizes human,mouse,rat antigen. The ADCY3 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 19492-1-AP(ADCY3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 19492-1-AP(ADCY3 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue