Tissue expression
Cell line expression
Protein structure
PMS1
PMS1 homolog 1, mismatch repair system componentMLH2, PMSL1
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| NSJ Bioreagents | Monoclonal |
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| Invitrogen Antibodies | Monoclonal |
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| Santa Cruz Biotechnology | 2 references | Polyclonal (Antigen purified) |
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| Proteintech Group | 2 references | Polyclonal |
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| Antibodies.com | Monoclonal |
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