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- References [7]
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- Product number
- ABIN400795 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 58-81) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant human PMS2 corresponding to the first 133 amino acid residues of theprotein
- Description
- Protein chromatography
- Reactivity
- Human, Mouse, Rat, Hamster
- Host
- Mouse
- Epitope
- AA 58-81
- Isotype
- IgG
- Antibody clone number
- 349-29-5-2
- Vial size
- 0.1 mg
- Concentration
- 1.38 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody at 2°C to 8°C up to one month or (in aliquots) at -20°C to -70°C forlonger. Avoid repeated freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Shelf life: one year from despatch.
Submitted references ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage.
Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation.
Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer.
Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.
Distal 2q duplication: report of two familial cases and an attempt to define a syndrome.
Luo Y, Lin FT, Lin WC
Molecular and cellular biology 2004 Jul;24(14):6430-44
Molecular and cellular biology 2004 Jul;24(14):6430-44
Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation.
Nakagawa H, Lockman JC, Frankel WL, Hampel H, Steenblock K, Burgart LJ, Thibodeau SN, de la Chapelle A
Cancer research 2004 Jul 15;64(14):4721-7
Cancer research 2004 Jul 15;64(14):4721-7
Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer.
de Jong AE, van Puijenbroek M, Hendriks Y, Tops C, Wijnen J, Ausems MG, Meijers-Heijboer H, Wagner A, van Os TA, Bröcker-Vriends AH, Vasen HF, Morreau H
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Feb 1;10(3):972-80
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Feb 1;10(3):972-80
Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
Yuan ZQ, Gottlieb B, Beitel LK, Wong N, Gordon PH, Wang Q, Puisieux A, Foulkes WD, Trifiro M
Human mutation 2002 Feb;19(2):108-13
Human mutation 2002 Feb;19(2):108-13
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J
Genes & development 2000 Apr 15;14(8):927-39
Genes & development 2000 Apr 15;14(8):927-39
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.
Nicolaides NC, Papadopoulos N, Liu B, Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM
Nature 1994 Sep 1;371(6492):75-80
Nature 1994 Sep 1;371(6492):75-80
Distal 2q duplication: report of two familial cases and an attempt to define a syndrome.
Zankl M, Schwanitz G, Schmid P, Zankl H, Dockter G, Rodewald A, Zang KD, Grosse KP
American journal of medical genetics 1979;4(1):5-16
American journal of medical genetics 1979;4(1):5-16
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