ACOT8

The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. [provided by RefSeq, Oct 2010]

Description

acyl-CoA thioesterase 8

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

20:q13.12 (45841721 - 45857405)

Ensembl ID

ENSG00000101473  (ver. 99.38)

Orthologs

Mouse Acot8: ENSMUSG00000017307

UniProt

O14734

neXtProt

NX_O14734

Human splice variants
Mouse splice variants