NB500-138
antibody from Novus Biologicals
Targeting: MAPK14
CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15
Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB500-138 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB500-138, RRID:AB_2297479
- Product name
- Rabbit Polyclonal p38 alpha Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specific for the ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182. Immunolabeling is blocked by preadsorption of the antibody with the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Contribution of Increased Expression of Yin Yang 2 to Development of Cardiomyopathy.
Tumor Necrosis Factor-α-Mediated Metaplastic Inhibition of LTP Is Constitutively Engaged in an Alzheimer's Disease Model.
EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases.
Nonylphenol attenuates SOCS3 expression and M1 polarization in lipopolysaccharide-treated rat splenic macrophages.
RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways.
Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia.
c-Jun NH2 -terminal kinase is a critical node in the death of CD4+ CD8+ thymocytes during Salmonella enterica serovar Typhimurium infection.
GSTT1 is upregulated by oxidative stress through p38-MK2 signaling pathway in human granulosa cells: possible association with mitochondrial activity.
Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.
Zhang Y, Beketaev I, Segura AM, Yu W, Xi Y, Chang J, Ma Y, Wang J
Frontiers in molecular biosciences 2020;7:35
Frontiers in molecular biosciences 2020;7:35
Tumor Necrosis Factor-α-Mediated Metaplastic Inhibition of LTP Is Constitutively Engaged in an Alzheimer's Disease Model.
Singh A, Jones OD, Mockett BG, Ohline SM, Abraham WC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Nov 13;39(46):9083-9097
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Nov 13;39(46):9083-9097
EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases.
Ohm AM, Affandi T, Reyland ME
The Journal of biological chemistry 2019 Mar 22;294(12):4488-4497
The Journal of biological chemistry 2019 Mar 22;294(12):4488-4497
Nonylphenol attenuates SOCS3 expression and M1 polarization in lipopolysaccharide-treated rat splenic macrophages.
Pal S, Nath P, Biswas S, Mukherjee U, Maitra S
Ecotoxicology and environmental safety 2019 Jun 15;174:574-583
Ecotoxicology and environmental safety 2019 Jun 15;174:574-583
RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways.
Wu XM, Chen WQ, Hu YW, Cao L, Nie P, Chang MX
Frontiers in immunology 2018;9:726
Frontiers in immunology 2018;9:726
Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia.
Brzeszczyńska J, Meyer A, McGregor R, Schilb A, Degen S, Tadini V, Johns N, Langen R, Schols A, Glass DJ, Roubenoff R, Ross JA, Fearon KCH, Greig CA, Jacobi C
Journal of cachexia, sarcopenia and muscle 2018 Feb;9(1):93-105
Journal of cachexia, sarcopenia and muscle 2018 Feb;9(1):93-105
c-Jun NH2 -terminal kinase is a critical node in the death of CD4+ CD8+ thymocytes during Salmonella enterica serovar Typhimurium infection.
Deobagkar-Lele M, Victor ES, Nandi D
European journal of immunology 2014 Jan;44(1):137-49
European journal of immunology 2014 Jan;44(1):137-49
GSTT1 is upregulated by oxidative stress through p38-MK2 signaling pathway in human granulosa cells: possible association with mitochondrial activity.
Ito M, Imai M, Muraki M, Miyado K, Qin J, Kyuwa S, Yoshikawa Y, Hosoi Y, Saito H, Takahashi Y
Aging 2011 Dec;3(12):1213-23
Aging 2011 Dec;3(12):1213-23
Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.
Ito M, Miyado K, Nakagawa K, Muraki M, Imai M, Yamakawa N, Qin J, Hosoi Y, Saito H, Takahashi Y
Molecular human reproduction 2010 Dec;16(12):928-37
Molecular human reproduction 2010 Dec;16(12):928-37
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: p38 [p Thr180, p Tyr182] Antibody [NB500-138] - Western blot of HeLa cell lysates that had been treated with UV or untreated (Control) showing specific immunolabeling of the ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: p38 [p Thr180, p Tyr182] Antibody [NB500-138] - Hela cell lysates that had been treated with UV or untreated (Control) showing specific immunolabeling of the -39 kDa p38 MAPK protein phosphorylated at Thr180/Tyr182.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: p38 [p Thr180, p Tyr182] Antibody [NB500-138] - Immunostaining of human breast cancer tissue showing p38 when phosphorylated at Thr180/Tyr182 in red.