ABIN359422
antibody from antibodies-online
Targeting: MAPK14
CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- ABIN359422 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (Tyr322) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y322 of human MAPK14.
- Description
- Protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Tyr322
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody at 2 - 8°C up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.
P38 MAP kinase is activated at early stages in Alzheimer's disease brain.
p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation.
Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.
p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts.
Yustein JT, Xia L, Kahlenburg JM, Robinson D, Templeton D, Kung HJ
Oncogene 2003 Sep 18;22(40):6129-41
Oncogene 2003 Sep 18;22(40):6129-41
P38 MAP kinase is activated at early stages in Alzheimer's disease brain.
Sun A, Liu M, Nguyen XV, Bing G
Experimental neurology 2003 Oct;183(2):394-405
Experimental neurology 2003 Oct;183(2):394-405
p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation.
Dean JL, Sarsfield SJ, Tsounakou E, Saklatvala J
The Journal of biological chemistry 2003 Oct 10;278(41):39470-6
The Journal of biological chemistry 2003 Oct 10;278(41):39470-6
Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.
Cheung PC, Campbell DG, Nebreda AR, Cohen P
The EMBO journal 2003 Nov 3;22(21):5793-805
The EMBO journal 2003 Nov 3;22(21):5793-805
p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts.
Frevel MA, Bakheet T, Silva AM, Hissong JG, Khabar KS, Williams BR
Molecular and cellular biology 2003 Jan;23(2):425-36
Molecular and cellular biology 2003 Jan;23(2):425-36
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of MAPK14(arrow) using rabbit polyclonal MAPK14 Antibody (Y322) (AP13906PU-N). 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected with the MAPK14 gene (Lane 2) (Origene Technologies).
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of MAPK14 Antibody (Y322) (AP13906PU-N) in HepG2 cell line lysates (35 μg/lane). MAPK14 (arrow) was detected using the purified Pab (1:60 dilution).