abx031985

antibody from Abbexa

Targeting: MAPK14 CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15

No application information provided.

Antibody Data

Product number

abx031985

Provider

Abbexa

Product name

Mitogen-Activated Protein Kinase 14 Phospho-Tyr323 (MAPK14 pY323) Antibody

Antibody type

Polyclonal

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.