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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [10]
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- Product number
- ABIN117983 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 310-325) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody was affinity purified from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to aa 310-325 of rabbit MAPKAP Kinase 2 conjugated to KLH using maleimide. A terminal cysteine residue was added to facilitate coupling.
- Description
- Affinity Purified
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Hamster, Rabbit, Xenopus, Zebrafish
- Host
- Rabbit
- Antigen sequence
M-T-S-A-L-A-T-M-R-V-D-Y-E-Q-I-K- Epitope
- AA 310-325
- Vial size
- 0.1 mg
- Concentration
- 0.9 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light.
Submitted references Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan.
[Mechanism of action of xipamide and its classification as a "low ceiling diuretic". Pharmacodynamic-pharmacokinetic studies in healthy volunteers and in kidney and liver patients].
Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2.
Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia.
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels.
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs.
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.
The primary structure of a human MAP kinase activated protein kinase 2.
The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2.
Concejero A, Chen CL, Wang CC, Wang SH, Lin CC, Liu YW, Yang CH, Yong CC, Lin TS, Jawan B, Huang TL, Cheng YF, Eng HL
Transplantation 2008 Feb 15;85(3):398-406
Transplantation 2008 Feb 15;85(3):398-406
[Mechanism of action of xipamide and its classification as a "low ceiling diuretic". Pharmacodynamic-pharmacokinetic studies in healthy volunteers and in kidney and liver patients].
Knauf H, Mutschler E
Arzneimittel-Forschung 2005;55(1):1-14
Arzneimittel-Forschung 2005;55(1):1-14
Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2.
Cheng TJ, Tseng YF, Chang WM, Chang MD, Lai YK
Journal of cellular biochemistry 2003 Jun 1;89(3):589-602
Journal of cellular biochemistry 2003 Jun 1;89(3):589-602
Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia.
Verma A, Deb DK, Sassano A, Kambhampati S, Wickrema A, Uddin S, Mohindru M, Van Besien K, Platanias LC
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 15;168(12):5984-8
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 15;168(12):5984-8
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels.
Neininger A, Kontoyiannis D, Kotlyarov A, Winzen R, Eckert R, Volk HD, Holtmann H, Kollias G, Gaestel M
The Journal of biological chemistry 2002 Feb 1;277(5):3065-8
The Journal of biological chemistry 2002 Feb 1;277(5):3065-8
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs.
Rousseau S, Morrice N, Peggie M, Campbell DG, Gaestel M, Cohen P
The EMBO journal 2002 Dec 2;21(23):6505-14
The EMBO journal 2002 Dec 2;21(23):6505-14
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.
Kotlyarov A, Neininger A, Schubert C, Eckert R, Birchmeier C, Volk HD, Gaestel M
Nature cell biology 1999 Jun;1(2):94-7
Nature cell biology 1999 Jun;1(2):94-7
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.
Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR
Cell 1994 Sep 23;78(6):1027-37
Cell 1994 Sep 23;78(6):1027-37
The primary structure of a human MAP kinase activated protein kinase 2.
Zu YL, Wu F, Gilchrist A, Ai Y, Labadia ME, Huang CK
Biochemical and biophysical research communications 1994 Apr 29;200(2):1118-24
Biochemical and biophysical research communications 1994 Apr 29;200(2):1118-24
The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2.
Stokoe D, Caudwell B, Cohen PT, Cohen P
The Biochemical journal 1993 Dec 15;296 ( Pt 3):843-9
The Biochemical journal 1993 Dec 15;296 ( Pt 3):843-9
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