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- References [14]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 13949-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MAPKAPK2 antibody
- Antibody type
- Polyclonal
- Description
- MAPKAPK2 antibody (Cat. #13949-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification and validation of the VEGF/p38MAPK/HSP27 pro-tumor inflammatory pathway: screening of active components from Patrinia villosa and evaluation of their drug-likeness.
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma.
iRGD-modified co-loaded curcumin piperine liposomes inhibit angiogenesis in non-small cell lung cancer through the VEGFR2/P38/MK2 signaling axis.
Functional profiling of serine, threonine and tyrosine sites.
MAPK-activated protein kinase 2 is associated with poor prognosis of glioma patients and immune inhibition in glioma.
NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38(MAPK)/MK2 phosphorylation in S. typhimurium infection.
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
L-Theanine mediates the p38MAPK signaling pathway to alleviate heat-induced oxidative stress and inflammation in mice.
MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal.
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin.
p38 MAPK-DRP1 signaling is involved in mitochondrial dysfunction and cell death in mutant A53T α-synuclein model of Parkinson's disease.
Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2.
The p38 mitogen activated protein kinase regulates β-amyloid protein internalization through the α7 nicotinic acetylcholine receptor in mouse brain.
Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway.
Li X, Ju Y, Yang X, Li T, Wang S, Bao Y, Meng X
Frontiers in immunology 2025;16:1631031
Frontiers in immunology 2025;16:1631031
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma.
Qi R, Fang C, Liu P, Gu W, Shi C, Zhang G, Qiu F
Frontiers in genetics 2025;16:1615018
Frontiers in genetics 2025;16:1615018
iRGD-modified co-loaded curcumin piperine liposomes inhibit angiogenesis in non-small cell lung cancer through the VEGFR2/P38/MK2 signaling axis.
Huang X, Chen Y, Chen J, Lin J, Zhuang Y, Huang M, Yu H, Wang M, Wang Y, Wang Y
Discover oncology 2025 Nov 7;16(1):2056
Discover oncology 2025 Nov 7;16(1):2056
Functional profiling of serine, threonine and tyrosine sites.
Li Y, Xu T, Ma H, Yue D, Lamao Q, Liu Y, Zhou Z, Wei W
Nature chemical biology 2025 Apr;21(4):532-543
Nature chemical biology 2025 Apr;21(4):532-543
MAPK-activated protein kinase 2 is associated with poor prognosis of glioma patients and immune inhibition in glioma.
Sun J, Wu S, Zhao W, Xue S, Zhang L, Ren J
Frontiers in oncology 2024;14:1307992
Frontiers in oncology 2024;14:1307992
NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38(MAPK)/MK2 phosphorylation in S. typhimurium infection.
Deng Q, Yang S, Huang K, Zhu Y, Sun L, Cao Y, Dong K, Li Y, Wu S, Huang R
iScience 2024 Apr 19;27(4):109339
iScience 2024 Apr 19;27(4):109339
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Wang Z, Yin L, Qi Y, Zhang J, Zhu H, Tang J
Frontiers in microbiology 2022;13:934786
Frontiers in microbiology 2022;13:934786
L-Theanine mediates the p38MAPK signaling pathway to alleviate heat-induced oxidative stress and inflammation in mice.
Liu K, Liu E, Lin L, Hu Y, Yuan Y, Xiao W
Food & function 2022 Feb 21;13(4):2120-2130
Food & function 2022 Feb 21;13(4):2120-2130
MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal.
Zhang Y, Ding H, Wang X, Wang X, Wan S, Xu A, Gan R, Ye SD
Cell reports 2021 Nov 2;37(5):109949
Cell reports 2021 Nov 2;37(5):109949
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin.
Sun F, Liu Y, Gong T, Pan Q, Xiang T, Zhao J, Tang Y, Chen H, Han Y, Song M, Huang Y, Li H, Chen Y, Yang C, Yang J, Wang Q, Li Y, He J, Weng D, Peng R, Xia J
Cell death & disease 2021 Nov 18;12(12):1093
Cell death & disease 2021 Nov 18;12(12):1093
p38 MAPK-DRP1 signaling is involved in mitochondrial dysfunction and cell death in mutant A53T α-synuclein model of Parkinson's disease.
Gui C, Ren Y, Chen J, Wu X, Mao K, Li H, Yu H, Zou F, Li W
Toxicology and applied pharmacology 2020 Feb 1;388:114874
Toxicology and applied pharmacology 2020 Feb 1;388:114874
Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2.
Wang R, Liu H, Shao Y, Wang K, Yin S, Qiu Y, Wu H, Liu E, Wang T, Gao X, Yu H
Molecular cancer research : MCR 2019 Dec;17(12):2469-2479
Molecular cancer research : MCR 2019 Dec;17(12):2469-2479
The p38 mitogen activated protein kinase regulates β-amyloid protein internalization through the α7 nicotinic acetylcholine receptor in mouse brain.
Ma KG, Lv J, Yang WN, Chang KW, Hu XD, Shi LL, Zhai WY, Zong HF, Qian YH
Brain research bulletin 2018 Mar;137:41-52
Brain research bulletin 2018 Mar;137:41-52
Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway.
Wang Q, Yang K, Han B, Sheng B, Yin J, Pu A, Li L, Sun L, Yu M, Qiu Y, Xiao W, Yang H
International journal of molecular medicine 2018 Feb;41(2):868-876
International journal of molecular medicine 2018 Feb;41(2):868-876
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13949-1-AP(MAPKAPK2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAPKAPK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MAPKAPK2. This antibody recognizes human, mouse antigen. The MAPKAPK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
