TAB-031

antibody from Creative Biolabs

Targeting: IL5 EDF, IL-5, TRF

No application information provided.

Antibody Data

Product number

TAB-031

Provider

Creative Biolabs

Product name

Anti-Human IL5 Recombinant Antibody (Mepolizumab)

Antibody type

Monoclonal

Description

Recombinant monoclonal antibody to Human IL5. Mepolizumab (proposed trade name Bosatria) is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5), and is used to treat certain kinds of asthma and white blood cell diseases. Recent studies have concluded that mepolizumab may improve exacerbations in patients with severe eosinophilic asthma, an adult-onset asthma which represents less than 5% of all asthma. IL-5 is a chemical messenger in the immune system that stimulates the growth of eosinophils. In eosinophilic asthma, eosinophils are present in the lungs. When mepolizumab was given to people with eosinophilic asthma, it eliminated eosinophils from the bloodstream,and reduced eosinophils in the lungs and bone marrow. Mepolizumab also reduced the number of asthma exacerbations, and reduced the need for corticosteroids.

Reactivity

Human

Storage

Store at -20¡ãC for long-term storage. Store at 2-8¡ãC for up to one month. Avoid freeze/thaw cycles.