504308

antibody from BioLegend

Targeting: IL5 EDF, IL-5, TRF

Western blot (Recommended by provider)

ELISA (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Other assay (Recommended by provider)

Antibody Data

Product number

504308

Provider

BioLegend

Proper citation

BioLegend Cat#504308, RRID:AB_2296161

Product name

LEAF™ Purified anti-mouse/human IL-5 [TRFK5]

Antibody type

Monoclonal

Antigen

Partially-Purified T cell clone supernatant

Description

IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Reactivity

Human, Mouse, Guinea Pig

Host

Rat

Conjugate

Unconjugated

Isotype

IgG

Vial size

500 µg

Concentration

1 mg/ml

Storage

The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.