MAB205

antibody from R&D Systems

Targeting: IL5 EDF, IL-5, TRF

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB205

Provider

R&D Systems

Product name

Anti-Human IL-5 Monoclonal Antibody (Clone 14611)

Antibody type

Monoclonal

Antigen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-5, Ile20-Ser134

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P05113


Isotype

IgG

Vial size

500 µg

References

Submitted references

Inhibition of interleukin-5 induced false positive anti-drug antibody responses against mepolizumab through the use of a competitive blocking antibody.

Liao K, Meyer E, Lee TN, Loercher A, Sikkema D
Journal of immunological methods 2017 Feb;441:15-23

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Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.

van Meijgaarden KE, Haks MC, Caccamo N, Dieli F, Ottenhoff TH, Joosten SA
PLoS pathogens 2015 Mar;11(3):e1004671

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Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects.

Hellman C, Halldén G, Hylander B, Lundahl J
Clinical and experimental immunology 2003 Jan;131(1):75-81

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Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects.

Hellman C, Halldén G, Hylander B, Lundahl J
Clinical and experimental immunology 2003 Jan;131(1):75-81