66890-1-Ig

antibody from Proteintech Group

Targeting: JAG1 AGS, AHD, AWS, CD339, HJ1, JAGL1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

66890-1-Ig

Provider

Proteintech Group

Product name

Jagged1 antibody

Antibody type

Monoclonal

Description

Jagged1 antibody (Cat. #66890-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgA

Antibody clone number

2A7D11

Vial size

20ul, 150ul

References

Submitted references

LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling.

Lin L, Li X, Guo W, Xie J, Li X, Guan X, Zhao C, Yin H, Xu H
Cell reports. Medicine 2026 Mar 17;7(3):102658

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DOT1L promotes phenotypic transition of vascular smooth muscle cells following vascular injury in diabetes through activation of the FGFR4/PI3K/AKT/Jag/Notch signaling pathway.

Zhang J, Wu D, Cheng C, Yang Z, Chen Z, Liu L, Li W, Wang W, Huang C, Yang J
Cellular signalling 2026 Feb;138:112223

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Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.

Wu Y, Yuan X, Ma J, Xu L, Li M, Zhao G, Wang Y
Veterinary research 2025 Sep 25;56(1):185

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Inhibition of liver cancer cell growth by metabolites S-adenosylmethionine and nicotinic acid originating from liver progenitor cells.

Liu WM, Chen CY, Ma HQ, Zhang QQ, Zhou X, Wu YL, Huang WJ, Qi XS, Zhang YX, Tang D, Sun HY, Wu HP, Jiao YF, He ZY, Yu WF, Yan HX
Journal of gastroenterology 2025 Jun;60(6):754-769

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Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.

Ye L, Zheng X, Yang Y, Lyu Y
Biomedical reports 2025 Jul;23(1):111

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Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway.

Lee SH, Kang TY, Shang X, Levchenko A
Cell systems 2025 Jul 16;16(7):101321

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The role of estrogen receptors (ERs)-Notch pathway in thyroid toxicity induced by Di-2-ethylhexyl phthalate (DEHP) exposure: Population data and in vitro studies.

Zhang X, Zhang Y, Feng X, Zhao H, Ye H, Fang X, Cui J, Qi W, Ye L
Ecotoxicology and environmental safety 2024 Jan 1;269:115727

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Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.

Wang Z, Bi M, Zhe X, Wang X, Dai B, Han X, Ren B, Liang H, Liu D
Cell death discovery 2024 Feb 22;10(1):95

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The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma.

Leung YK, Lee SG, Wang J, Guruvaiah P, Rusch NJ, Ho SM, Park C, Kim K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2308539

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STK214947, a novel indole alkaloids, inhibits HeLa and SK-HEP-1 cells survival and EMT process by blocking the Notch3 and Akt signals.

Xu Z, Yuan Y, Liu J, Li C, Chen K, Wang F, Li G
Anti-cancer drugs 2024 Apr 1;35(4):325-332

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Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.

Shi B, Ge F, Cai L, Yang Y, Guo X, Wu R, Fan Z, Cao B, Wang N, Si Y, Lin X, Dong W, Sun H
Frontiers in immunology 2023;14:1247288

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Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.

Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X
Molecular oncology 2023 Apr;17(4):695-709

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IL-7-Treated Periodontal Ligament Cells Regulate Local Immune Homeostasis by Modulating Treg/Th17 Cell Polarization.

Yu XY, Zhang ZQ, Huang JC, Lin JY, Cai XP, Liu CF
Frontiers in medicine 2022;9:754341

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A comprehensive role evaluation and mechanism exploration of POGLUT2 in pan-cancer.

Xu X, Xie G, Xie M, Liu Q
Frontiers in oncology 2022;12:962540

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Effects of Tricholoma matsutake (Agaricomycetes) Extracts on Promoting Proliferation of HaCaT Cells and Accelerating Mice Wound Healing.

Zhu W, Chen Y, Qu K, Lai C, Lu Z, Yang F, Ju T, Wang Z
International journal of medicinal mushrooms 2021;23(9):45-53

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Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.

Zhang X, Xu X, Zhang Z, Xue C, Kong Z, Wu S, Yun X, Fu Y, Zhu C, Qin X
International journal of biological sciences 2021;17(3):768-780

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Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.

Cheng L, Xie M, Qiao W, Song Y, Zhang Y, Geng Y, Xu W, Wang L, Wang Z, Huang K, Dong N, Sun Y
Communications biology 2021 Sep 6;4(1):1039

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LncRNA TDRG1/miR-214-5p axis affects preeclampsia by modulating trophoblast cells.

Gong F, Cheng H, Shi Y, Cui L, Jia G
Cell biochemistry and function 2020 Jun;38(4):352-361

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miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.

Gong F, Chai W, Wang J, Cheng H, Shi Y, Cui L, Jia G
Acta histochemica 2020 Apr;122(3):151527