Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1003224 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- SOCS1 antibody was raised against an 17 amino acid peptide from near the amino terminus of human SOCS1.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation.
Controlling cytokine signaling by constitutive inhibitors.
The SOCS box: a tale of destruction and degradation.
Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.
Mansell A, Smith R, Doyle SL, Gray P, Fenner JE, Crack PJ, Nicholson SE, Hilton DJ, O'Neill LA, Hertzog PJ
Nature immunology 2006 Feb;7(2):148-55
Nature immunology 2006 Feb;7(2):148-55
Controlling cytokine signaling by constitutive inhibitors.
Rakesh K, Agrawal DK
Biochemical pharmacology 2005 Sep 1;70(5):649-57
Biochemical pharmacology 2005 Sep 1;70(5):649-57
The SOCS box: a tale of destruction and degradation.
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ
Trends in biochemical sciences 2002 May;27(5):235-41
Trends in biochemical sciences 2002 May;27(5):235-41
Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.
O'Shea JJ, Gadina M, Schreiber RD
Cell 2002 Apr;109 Suppl:S121-31
Cell 2002 Apr;109 Suppl:S121-31
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