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Learn14961-1-AP
antibody from Proteintech Group
Targeting: RAD51
BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA
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- Antibody Data
- Antigen structure
- References [104]
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- Validations
- Western blot [1]
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- Product number
- 14961-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14961-1-AP, RRID:AB_2177083
- Product name
- RAD51 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAD51 antibody (Cat. #14961-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage-Induced Mitochondrial Apoptosis and Parthanatos-Like Cell Death.
Cholangiocytes' primary cilia regulate DNA damage response and repair.
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation.
KAT2A-driven succinylation of SRSF11 enforces spliceosome-mediated RAD52 splicing to promote homologous recombination and radioresistance in hepatocellular carcinoma.
CNOT7 facilitates radiation resistance in colorectal cancer through TRIM21/XRCC6-mediated non-homologous end joining repair.
Phospho-TRIM21 orchestrates RPA2 ubiquitination switch to promote homologous recombination and tumor radio/chemo-resistance.
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma.
Combined Ribociclib and NU7026 administration enhances radio-sensitivity by inhibiting DNA repair in prostate cancer.
Effect of defective H2B ubiquitination on the malignancy and repair of DNA double breaks and its significance in lung adenocarcinoma.
Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair.
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Crotonylation of MCM6 enhances chemotherapeutics sensitivity of breast cancer via inducing DNA replication stress.
DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance.
Cholangiocytes' Primary Cilia Regulate DNA Damage Response and Repair.
Bavachinin exerts anti-tumor effects by activating TLR4/STING axis-dependent PANoptosis and synergistically enhances chemosensitivity in endometrial cancer.
Histone H3 acetylation reverses radioresistance in breast cancers through BRD3-mediated inhibition of RAD51 and inducing ferroptosis.
PCAF-mediated acetylation regulates RAD51 dynamic localization on chromatin during HR repair.
DNA/RNA-binding protein KIN17 supports esophageal cancer progression via resolving noncanonical STING activation induced by R-loop.
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.
Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma.
Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS-PD-L1 pathway in cervical cancer development.
ZNF131-BACH1 transcriptionally accelerates RAD51-dependent homologous recombination repair and therapy-resistance of non-small-lung cancer cells by preventing their degradation from CUL3.
Bevacizumab increases the sensitivity of olaparib to homologous recombination-proficient ovarian cancer by suppressing CRY1 via PI3K/AKT pathway.
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation.
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Immune Checkpoint-Modulating Photosensitizer That Targets BRD4 for Cancer Photoimmunotherapy.
YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression.
Reconstitution of the antagonistic effect between C1orf112/FIRRM-FIGNL1 and BRCA2 on RAD51 filament stabilization.
COMMD10 inhibited DNA damage to promote the progression of gastric cancer.
NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer.
Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication.
The neuroprotective effects of caffeic acid phenethyl ester against methamphetamine-induced neurotoxicity.
IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway.
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma.
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription.
Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor.
The Compromised Fanconi Anemia Pathway in Prelamin A-Expressing Cells Contributes to Replication Stress-Induced Genomic Instability.
Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.
Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.
Identification of key enzalutamide-resistance-related genes in castration-resistant prostate cancer and verification of RAD51 functions.
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer.
Modulation of cell cycle increases CRISPR-mediated homology-directed DNA repair.
Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair.
Creatine kinase brain-type regulates BCAR1 phosphorylation to facilitate DNA damage repair.
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins.
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
Transcriptionally regulated miR-26a-5p may act as BRCAness in Triple-Negative Breast Cancer.
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Cancer-Associated Fibroblasts Promote Radioresistance of Breast Cancer Cells via the HGF/c-Met Signaling Pathway.
Paclitaxel sensitizes homologous recombination-proficient ovarian cancer cells to PARP inhibitor via the CDK1/BRCA1 pathway.
Antitumor efficacy of a recombinant EGFR-targeted fusion protein conjugate that induces telomere shortening and telomerase downregulation.
ERCC6L facilitates the progression of laryngeal squamous cell carcinoma by the binding of FOXM1 and KIF4A.
Regulation of DNA damage response by trimeric G-proteins.
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.
C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair.
SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA.
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
The Pathogenic R3052W BRCA2 Variant Disrupts Homology-Directed Repair by Failing to Localize to the Nucleus.
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair.
KIAA1529 regulates RAD51 expression to confer PARP inhibitors resistance in ovarian cancer.
Identification of Candidate Genes in Breast Cancer Induced by Estrogen Plus Progestogens Using Bioinformatic Analysis.
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [Ca(2+)](m)-PDP1-PDH-histone acetylation retrograde signaling.
Predictive value of RAD51 on the survival and drug responsiveness of ovarian cancer.
Hollow PtCo alloy nanospheres as a high-Z and oxygen generating nanozyme for radiotherapy enhancement in non-small cell lung cancer.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer.
Inhibition of survivin induces spindle disorganization, chromosome misalignment, and DNA damage during mouse embryo development.
CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos.
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium.
Rab1A promotes cancer metastasis and radioresistance through activating GSK-3β/Wnt/β-catenin signaling in nasopharyngeal carcinoma.
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers.
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin.
RDM1 promotes critical processes in breast cancer tumorigenesis.
LncRNA lnc-RI regulates homologous recombination repair of DNA double-strand breaks by stabilizing RAD51 mRNA as a competitive endogenous RNA.
Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer Cells.
IER5 is involved in DNA Double-Strand Breaks Repair in Association with PAPR1 in Hela Cells.
Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib.
Triptolide induces DNA breaks, activates caspase-3-dependent apoptosis and sensitizes B-cell lymphoma to poly(ADP-ribose) polymerase 1 and phosphoinositide 3-kinase inhibitors.
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone.
5-Azacytidine enhances the radiosensitivity of CNE2 and SUNE1 cells in vitro and in vivo possibly by altering DNA methylation.
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
Chen R, Han XH, Zhang Z, Han XJ, Xie J
iScience 2026 Mar 20;29(3):114916
iScience 2026 Mar 20;29(3):114916
Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage-Induced Mitochondrial Apoptosis and Parthanatos-Like Cell Death.
Fan H, Zhao H, Zhang P, Yu P, Ji Y, Chen G, Jin H, Liu Y, Liu J, Chen ZS, Lyu A, Liang X, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e11406
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e11406
Cholangiocytes' primary cilia regulate DNA damage response and repair.
Peixoto E, Pant K, Richard S, Popoca JP, Abrahante JE, Czaja W, Gradilone SA
American journal of physiology. Gastrointestinal and liver physiology 2025 Sep 1;329(3):G469-G483
American journal of physiology. Gastrointestinal and liver physiology 2025 Sep 1;329(3):G469-G483
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation.
Yu T, He Y, Li H, Sun Q, Chen M, Wang W, Li Q, Ju S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115653
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115653
KAT2A-driven succinylation of SRSF11 enforces spliceosome-mediated RAD52 splicing to promote homologous recombination and radioresistance in hepatocellular carcinoma.
Wu J, Yuan J, Liu Z, Zhou Y, Zhang B, Xu Y, Zeng Q, Wu Z, Kong L, Wang J, Zhang B, Yang J, Lv T, Shi Y, Yang J
Signal transduction and targeted therapy 2025 Nov 7;10(1):364
Signal transduction and targeted therapy 2025 Nov 7;10(1):364
CNOT7 facilitates radiation resistance in colorectal cancer through TRIM21/XRCC6-mediated non-homologous end joining repair.
Li Y, Cui L, Wang S, Zhao Q, Du F, Du S, Yu C, Xia M, Zhao S, Luan T, Liu Y, Cui B
Cell death & disease 2025 Nov 17;16(1):833
Cell death & disease 2025 Nov 17;16(1):833
Phospho-TRIM21 orchestrates RPA2 ubiquitination switch to promote homologous recombination and tumor radio/chemo-resistance.
Zhang J, Chen B, Xu F, Wang R, Zhao X, Yao Z, Zhang J, Zhou S, Xu A, Wu L, Zhao G
Oncogene 2025 May;44(16):1106-1117
Oncogene 2025 May;44(16):1106-1117
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Wang JQ, Liu XM, Zhu ZS, Li Z, Xie CZ, Qiao X, Feng YK, Xu JY
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma.
Liu B, Li W, Zhang W, Feng C, Wan L, He S, Xu R, Fu Z, Liu Z, Xu H, Jin X, Tu C, Li Z
Signal transduction and targeted therapy 2025 May 21;10(1):165
Signal transduction and targeted therapy 2025 May 21;10(1):165
Combined Ribociclib and NU7026 administration enhances radio-sensitivity by inhibiting DNA repair in prostate cancer.
Sun J, Wang Y, Ma S, Zhang W, Yang L, Zhang B, Tang Q
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):7075-7085
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):7075-7085
Effect of defective H2B ubiquitination on the malignancy and repair of DNA double breaks and its significance in lung adenocarcinoma.
An Z, Yao N, Su W, Zhang W, Yang J, Guo Q, Zhang C, Tian P, Wan N, Wu C, Huang X, Song G, Jia J, Ren L
Scientific reports 2025 Jul 2;15(1):22576
Scientific reports 2025 Jul 2;15(1):22576
Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair.
Wei Y, Wang P, Zhao J, Fan X, Jiang J, Mu X, Wang Y, Yang A, Zhang R, Hu S, Guo Z
Cell death & disease 2025 Jan 26;16(1):47
Cell death & disease 2025 Jan 26;16(1):47
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Teng Y, Zhao H, Xue G, Zhang G, Huang Y, Guo W, Zou K, Zou L
Journal of translational medicine 2025 Jan 11;23(1):44
Journal of translational medicine 2025 Jan 11;23(1):44
Crotonylation of MCM6 enhances chemotherapeutics sensitivity of breast cancer via inducing DNA replication stress.
Song H, Guo Z, Xie K, Liu X, Yang X, Shen R, Wang D
Cell proliferation 2025 Feb;58(2):e13759
Cell proliferation 2025 Feb;58(2):e13759
DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance.
Xu Z, Nie C, Liao J, Ma Y, Zhou XA, Li X, Li S, Lin H, Luo Y, Cheng K, Mao Z, Zhang L, Pan Y, Chen Y, Wang W, Wang J
Molecular cell 2025 Feb 6;85(3):490-505.e11
Molecular cell 2025 Feb 6;85(3):490-505.e11
Cholangiocytes' Primary Cilia Regulate DNA Damage Response and Repair.
Peixoto E, Pant K, Richard S, Abrahante JE, Czaja W, Gradilone SA
bioRxiv : the preprint server for biology 2025 Feb 16;
bioRxiv : the preprint server for biology 2025 Feb 16;
Bavachinin exerts anti-tumor effects by activating TLR4/STING axis-dependent PANoptosis and synergistically enhances chemosensitivity in endometrial cancer.
Shu W, Chen G, Zhang J, Dong K, Zhou T, Cheng S, Zhang T, Zhang J, Li H, Yao Y, Yu S, Liu Y, Zhou X, Shen X, Wang H
Biochemical pharmacology 2025 Dec;242(Pt 2):117321
Biochemical pharmacology 2025 Dec;242(Pt 2):117321
Histone H3 acetylation reverses radioresistance in breast cancers through BRD3-mediated inhibition of RAD51 and inducing ferroptosis.
Ye DM, Qiu Y, Cai JM, Yu T, Zhang Y
Free radical biology & medicine 2025 Dec 16;241:760-772
Free radical biology & medicine 2025 Dec 16;241:760-772
PCAF-mediated acetylation regulates RAD51 dynamic localization on chromatin during HR repair.
Hou J, Shi M, Hong J, Liu Y, Song X, Rao H, Ma Y, Huang C, Hu Z, He L, Guo Z, Pan F
EMBO reports 2025 Aug;26(16):4100-4123
EMBO reports 2025 Aug;26(16):4100-4123
DNA/RNA-binding protein KIN17 supports esophageal cancer progression via resolving noncanonical STING activation induced by R-loop.
Wei Z, Zhao N, Kuang L, Cong J, Zheng S, Li Y, Liu Z
Signal transduction and targeted therapy 2025 Aug 15;10(1):256
Signal transduction and targeted therapy 2025 Aug 15;10(1):256
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.
Benedetti R, Di Crosta M, Gilardini Montani MS, D'Orazi G, Cirone M
Cell death discovery 2025 Apr 10;11(1):162
Cell death discovery 2025 Apr 10;11(1):162
Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma.
Chang Y, Yang J, Li Z, Zhu X, Jiang T, Wang Q, Yu M, Han B, Liu X
Chinese medical journal 2025 Apr 10;
Chinese medical journal 2025 Apr 10;
Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS-PD-L1 pathway in cervical cancer development.
Luo Y, Niu M, Liu Y, Zhang M, Deng Y, Mu D, Xu J, Hong S
Frontiers in pharmacology 2024;15:1450875
Frontiers in pharmacology 2024;15:1450875
ZNF131-BACH1 transcriptionally accelerates RAD51-dependent homologous recombination repair and therapy-resistance of non-small-lung cancer cells by preventing their degradation from CUL3.
Fan M, Liu Q, Ma X, Jiang Y, Wang Y, Jia S, Nie Y, Deng R, Zhou P, Zhang S, Jiang S, Guan M, Hou Y, Miao Y, Zhang Y, Zhang X
Theranostics 2024;14(18):7241-7264
Theranostics 2024;14(18):7241-7264
Bevacizumab increases the sensitivity of olaparib to homologous recombination-proficient ovarian cancer by suppressing CRY1 via PI3K/AKT pathway.
Iida Y, Yanaihara N, Yoshino Y, Saito M, Saito R, Tabata J, Kawabata A, Takenaka M, Chiba N, Okamoto A
Frontiers in oncology 2024;14:1302850
Frontiers in oncology 2024;14:1302850
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation.
Liu YP, He B, Wang WX, Pan WL, Jiao L, Yan JJ, Sun SC, Zhang Y
Mitochondrion 2024 Sep;78:101946
Mitochondrion 2024 Sep;78:101946
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Wang J, Wen Y, Zhang Y, Wang Z, Jiang Y, Dai C, Wu L, Leng D, He S, Bo X
Journal of advanced research 2024 Nov;65:329-343
Journal of advanced research 2024 Nov;65:329-343
Immune Checkpoint-Modulating Photosensitizer That Targets BRD4 for Cancer Photoimmunotherapy.
Li P, Du Y, Qiu J, Jiang Q, Chen W, Zhang X, Li G, Li D, Shan G
Journal of medicinal chemistry 2024 Nov 14;67(21):18930-18942
Journal of medicinal chemistry 2024 Nov 14;67(21):18930-18942
YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression.
Li X, Zhong H, Shi Q, Ruan R, Huang C, Wen Q, Zeng S, Xia Y, Zeng Q, Xiong J, Wang S, Chen J, Lei W, Deng J
Cellular and molecular life sciences : CMLS 2024 Mar 17;81(1):143
Cellular and molecular life sciences : CMLS 2024 Mar 17;81(1):143
Reconstitution of the antagonistic effect between C1orf112/FIRRM-FIGNL1 and BRCA2 on RAD51 filament stabilization.
Zhou Z, Yang H, Liang X, Zhou T, Liu Q, Wang J, Wang W
STAR protocols 2024 Mar 15;5(1):102791
STAR protocols 2024 Mar 15;5(1):102791
COMMD10 inhibited DNA damage to promote the progression of gastric cancer.
Liu X, Mao X, Zhu C, Liu H, Fang Y, Fu T, Fan L, Liu M, Xiong Z, Tang H, Hu P, Le A
Journal of cancer research and clinical oncology 2024 Jun 13;150(6):305
Journal of cancer research and clinical oncology 2024 Jun 13;150(6):305
NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer.
Yu M, Ni M, Xu F, Liu C, Chen L, Li J, Xia S, Diao Y, Chen J, Zhu J, Wu X, Tang M, Li J, Ke G
Molecular cancer 2024 Jul 5;23(1):139
Molecular cancer 2024 Jul 5;23(1):139
Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication.
Ming S, Zhang S, Xing J, Yang G, Zeng L, Wang J, Chu B
iScience 2024 Jul 19;27(7):110144
iScience 2024 Jul 19;27(7):110144
The neuroprotective effects of caffeic acid phenethyl ester against methamphetamine-induced neurotoxicity.
Yang B, Tan X, Chen Y, Lin J, Liang J, Yue X, Qiao D, Wang H, Du S
Ecotoxicology and environmental safety 2024 Jul 1;279:116497
Ecotoxicology and environmental safety 2024 Jul 1;279:116497
IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway.
Liu Z, Feng C, Li C, He T, Wu G, Fu C, Li H, Shen M, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23332
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23332
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma.
Hu J, Meng F, Lv L, Hong F, He Q, Zhu Q, Tian T, Chang N, Zhang S, Yi Q, Qian L
Cell death & disease 2024 Dec 27;15(12):933
Cell death & disease 2024 Dec 27;15(12):933
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription.
Yang S, Wang R, Liu L, Xu F, Zhao X, Yao Z, Zhang J, Cheng X, Xu A, Wu L, Zhao G
Cell death discovery 2024 Dec 18;10(1):496
Cell death discovery 2024 Dec 18;10(1):496
Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor.
Pu C, Liu Y, Lan S, Fan H, Liu L, Liu J, Guo Y
Bioorganic & medicinal chemistry 2024 Dec 1;115:117970
Bioorganic & medicinal chemistry 2024 Dec 1;115:117970
The Compromised Fanconi Anemia Pathway in Prelamin A-Expressing Cells Contributes to Replication Stress-Induced Genomic Instability.
Nie P, Zhang C, Wu F, Chen S, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2307751
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2307751
Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.
Xiao M, Cui X, Xu C, Xin L, Zhao J, Yang S, Hong B, Tan Y, Zhang J, Li X, Li J, Kang C, Fang C
CNS neuroscience & therapeutics 2024 Apr;30(4):e14698
CNS neuroscience & therapeutics 2024 Apr;30(4):e14698
Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.
Zhang Z, Liu Y, Xu Y, Xu Z, Jia J, Jin Y, Wang W, Liu L
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):576-585
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):576-585
Identification of key enzalutamide-resistance-related genes in castration-resistant prostate cancer and verification of RAD51 functions.
Xu W, Liu L, Cui Z, Li M, Ni J, Huang N, Zhang Y, Luo J, Sun L, Sun F
Open medicine (Warsaw, Poland) 2023;18(1):20230715
Open medicine (Warsaw, Poland) 2023;18(1):20230715
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
Kim H, Aliar K, Tharmapalan P, McCloskey CW, Kuttanamkuzhi A, Grünwald BT, Palomero L, Mahendralingam MJ, Waas M, Mer AS, Elliott MJ, Zhang B, Al-Zahrani KN, Langille ER, Parsons M, Narala S, Hofer S, Waterhouse PD, Hakem R, Haibe-Kains B, Kislinger T, Schramek D, Cescon DW, Pujana MA, Berman HK, Khokha R
Cell reports 2023 Oct 31;42(10):113256
Cell reports 2023 Oct 31;42(10):113256
KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer.
Wu Y, Chen S, Shao Y, Su Y, Li Q, Wu J, Zhu J, Wen H, Huang Y, Zheng Z, Chen X, Ju X, Huang S, Wu X, Hu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(31):e2304638
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(31):e2304638
Modulation of cell cycle increases CRISPR-mediated homology-directed DNA repair.
Li G, Yang X, Luo X, Wu Z, Yang H
Cell & bioscience 2023 Nov 25;13(1):215
Cell & bioscience 2023 Nov 25;13(1):215
Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair.
Yi J, Luo X, Xing J, Gedanken A, Lin X, Zhang C, Qiao G
Bioengineering & translational medicine 2023 May;8(3):e10507
Bioengineering & translational medicine 2023 May;8(3):e10507
Creatine kinase brain-type regulates BCAR1 phosphorylation to facilitate DNA damage repair.
Yang B, Zhang W, Sun L, Lu B, Yin C, Zhang Y, Jiang H
iScience 2023 May 19;26(5):106684
iScience 2023 May 19;26(5):106684
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins.
Zhang S, Ming SL, Zeng L, Wang LF, Zhang C, Zhu HS, Yang GY, Zhang GP, Chu BB, Wang J
Journal of medical virology 2023 Mar;95(3):e28591
Journal of medical virology 2023 Mar;95(3):e28591
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
Tan J, Wang W, Liu X, Xu J, Che Y, Liu Y, Hu J, Hu L, Li J, Zhou Q
Communications biology 2023 Jun 5;6(1):606
Communications biology 2023 Jun 5;6(1):606
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
Dey G, Bharti R, Braley C, Alluri R, Esakov E, Crean-Tate K, McCrae K, Joehlin-Price A, Rose PG, Lathia J, Gong Z, Reizes O
Journal of ovarian research 2023 Jun 27;16(1):122
Journal of ovarian research 2023 Jun 27;16(1):122
Transcriptionally regulated miR-26a-5p may act as BRCAness in Triple-Negative Breast Cancer.
Zhang Y, Lv L, Zheng R, Xie R, Yu Y, Liao H, Chen J, Zhang B
Breast cancer research : BCR 2023 Jun 26;25(1):75
Breast cancer research : BCR 2023 Jun 26;25(1):75
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Wei Y, Xiao G, Xu H, Sun X, Shi Y, Wang F, Kang J, Peng J, Zhou F
The FEBS journal 2023 Jul;290(14):3629-3645
The FEBS journal 2023 Jul;290(14):3629-3645
Cancer-Associated Fibroblasts Promote Radioresistance of Breast Cancer Cells via the HGF/c-Met Signaling Pathway.
Wang B, Liu W, Liu C, Du K, Guo Z, Zhang G, Huang Z, Lin S, Cen B, Tian Y, Yuan Y, Bu J
International journal of radiation oncology, biology, physics 2023 Jul 1;116(3):640-654
International journal of radiation oncology, biology, physics 2023 Jul 1;116(3):640-654
Paclitaxel sensitizes homologous recombination-proficient ovarian cancer cells to PARP inhibitor via the CDK1/BRCA1 pathway.
Yanaihara N, Yoshino Y, Noguchi D, Tabata J, Takenaka M, Iida Y, Saito M, Yanagida S, Iwamoto M, Kiyokawa T, Chiba N, Okamoto A
Gynecologic oncology 2023 Jan;168:83-91
Gynecologic oncology 2023 Jan;168:83-91
Antitumor efficacy of a recombinant EGFR-targeted fusion protein conjugate that induces telomere shortening and telomerase downregulation.
Tao HY, He SM, Zhao CY, Wang Y, Sheng WJ, Zhen YS
International journal of biological macromolecules 2023 Jan 31;226:1088-1099
International journal of biological macromolecules 2023 Jan 31;226:1088-1099
ERCC6L facilitates the progression of laryngeal squamous cell carcinoma by the binding of FOXM1 and KIF4A.
Cui M, Chang Y, Wang J, Wu J, Li G, Tan J
Cell death discovery 2023 Feb 2;9(1):41
Cell death discovery 2023 Feb 2;9(1):41
Regulation of DNA damage response by trimeric G-proteins.
Abd El-Hafeez AA, Sun N, Chakraborty A, Ear J, Roy S, Chamarthi P, Rajapakse N, Das S, Luker KE, Hazra TK, Luker GD, Ghosh P
iScience 2023 Feb 17;26(2):105973
iScience 2023 Feb 17;26(2):105973
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.
Shi M, Hou J, Liang W, Li Q, Shao S, Ci S, Shu C, Zhao X, Zhao S, Huang M, Wu C, Hu Z, He L, Guo Z, Pan F
EMBO reports 2023 Aug 3;24(8):e56437
EMBO reports 2023 Aug 3;24(8):e56437
C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair.
Zhou Z, Yang H, Liang X, Zhou T, Zhang T, Yang Y, Wang J, Wang W
Cell reports 2023 Aug 29;42(8):112907
Cell reports 2023 Aug 29;42(8):112907
SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA.
Zhang Q, Hao R, Chen H, Zhou G
Cell death discovery 2023 Aug 28;9(1):319
Cell death discovery 2023 Aug 28;9(1):319
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
Chang T, Lian Z, Ma S, Liang Z, Ma X, Wen X, Wang Y, Liu R
The Prostate 2023 Apr;83(5):470-486
The Prostate 2023 Apr;83(5):470-486
The Pathogenic R3052W BRCA2 Variant Disrupts Homology-Directed Repair by Failing to Localize to the Nucleus.
Jimenez-Sainz J, Krysztofiak A, Garbarino J, Rogers F, Jensen RB
Frontiers in genetics 2022;13:884210
Frontiers in genetics 2022;13:884210
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Wen X, Chen S, Chen X, Qiu H, Wang W, Zhang N, Liu W, Wang T, Ding X, Zhang L
Frontiers in oncology 2022;12:887068
Frontiers in oncology 2022;12:887068
BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair.
Jimenez-Sainz J, Mathew J, Moore G, Lahiri S, Garbarino J, Eder JP, Rothenberg E, Jensen RB
eLife 2022 Sep 13;11
eLife 2022 Sep 13;11
KIAA1529 regulates RAD51 expression to confer PARP inhibitors resistance in ovarian cancer.
Qiao Y, Yu X, Zhou B, Zhang K, Huang J, Liao J
Translational oncology 2022 Oct;24:101497
Translational oncology 2022 Oct;24:101497
Identification of Candidate Genes in Breast Cancer Induced by Estrogen Plus Progestogens Using Bioinformatic Analysis.
Deng Y, Huang H, Shi J, Jin H
International journal of molecular sciences 2022 Oct 6;23(19)
International journal of molecular sciences 2022 Oct 6;23(19)
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Yu H, Wu S, Liu S, Li X, Gai Y, Lin H, Wang Y, Edwards H, Ge Y, Wang G
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
Li E, Xia M, Du Y, Long K, Ji F, Pan F, He L, Hu Z, Guo Z
eLife 2022 May 3;11
eLife 2022 May 3;11
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.
Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ
Nucleic acids research 2022 May 20;50(9):5129-5144
Nucleic acids research 2022 May 20;50(9):5129-5144
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Zhang X, Li T, Yang M, Du Q, Wang R, Fu B, Tan Y, Cao M, Chen Y, Wang Q, Hu R
Cell death & disease 2022 Feb 10;13(2):138
Cell death & disease 2022 Feb 10;13(2):138
Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [Ca(2+)](m)-PDP1-PDH-histone acetylation retrograde signaling.
Shi Y, Wang Y, Jiang H, Sun X, Xu H, Wei X, Wei Y, Xiao G, Song Z, Zhou F
Cell death & disease 2021 Sep 6;12(9):837
Cell death & disease 2021 Sep 6;12(9):837
Predictive value of RAD51 on the survival and drug responsiveness of ovarian cancer.
Feng Y, Wang D, Xiong L, Zhen G, Tan J
Cancer cell international 2021 May 5;21(1):249
Cancer cell international 2021 May 5;21(1):249
Hollow PtCo alloy nanospheres as a high-Z and oxygen generating nanozyme for radiotherapy enhancement in non-small cell lung cancer.
Li S, Sun W, Luo Y, Gao Y, Jiang X, Yuan C, Han L, Cao K, Gong Y, Xie C
Journal of materials chemistry. B 2021 Jun 16;9(23):4643-4653
Journal of materials chemistry. B 2021 Jun 16;9(23):4643-4653
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
Zhao X, Sun Y, Sun X, Li J, Shi X, Liang Z, Ma Y, Zhang X
DNA and cell biology 2021 Jul;40(7):895-905
DNA and cell biology 2021 Jul;40(7):895-905
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Zhang J, Yang S, Guan H, Zhou J, Gao Y
Journal of cellular and molecular medicine 2021 Feb;25(3):1688-1699
Journal of cellular and molecular medicine 2021 Feb;25(3):1688-1699
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Zhou S, Dai Z, Wang L, Gao X, Yang L, Wang Z, Wang Q, Liu Z
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Ni M, Li J, Zhao H, Xu F, Cheng J, Yu M, Ke G, Wu X
Oncogene 2021 Apr;40(15):2711-2724
Oncogene 2021 Apr;40(15):2711-2724
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, Li S, Zhang N, Ren J, Xiao Y, Liu X, Zhang J, Gong Y, Xie C
International journal of biological sciences 2020;16(12):2145-2158
International journal of biological sciences 2020;16(12):2145-2158
Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer.
Zhong L, Wang R, Wang Y, Peng S, Ma Y, Ding S, Yang H, Chen S, Luo X, Wang W
Neoplasia (New York, N.Y.) 2020 Sep;22(9):365-375
Neoplasia (New York, N.Y.) 2020 Sep;22(9):365-375
Inhibition of survivin induces spindle disorganization, chromosome misalignment, and DNA damage during mouse embryo development.
Pan MH, Ju JQ, Li XH, Xu Y, Wang JD, Ren YP, Lu X, Sun SC
Cell cycle (Georgetown, Tex.) 2020 Sep;19(17):2148-2157
Cell cycle (Georgetown, Tex.) 2020 Sep;19(17):2148-2157
CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos.
Ju JQ, Li XH, Pan MH, Xu Y, Sun MH, Xu Y, Sun SC
Cell proliferation 2020 Oct;53(10):e12895
Cell proliferation 2020 Oct;53(10):e12895
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Zhao L, Li R, Qiu JZ, Yu JB, Cao Y, Yuan RT
Molecular and cellular probes 2020 Oct;53:101577
Molecular and cellular probes 2020 Oct;53:101577
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q, Guo Z, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium.
Song L, Tang Z, Peng C, Yang Y, Guo C, Wang D, Guo L, Chen J, Liu C
BMC cancer 2020 Oct 21;20(1):1020
BMC cancer 2020 Oct 21;20(1):1020
Rab1A promotes cancer metastasis and radioresistance through activating GSK-3β/Wnt/β-catenin signaling in nasopharyngeal carcinoma.
Yang XZ, Chen XM, Zeng LS, Deng J, Ma L, Jin C, Wang R, Wang MH, Wen YF, Wu XL, Wang HY, Cui SZ
Aging 2020 Oct 17;12(20):20380-20395
Aging 2020 Oct 17;12(20):20380-20395
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Luo W, Zhang H, Liang X, Xia R, Deng H, Yi Q, Lv L, Qian L
Oncology reports 2020 May;43(5):1692-1704
Oncology reports 2020 May;43(5):1692-1704
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers.
Zhao K, Wang X, Xue X, Li L, Hu Y
PLoS biology 2020 Mar;18(3):e3000666
PLoS biology 2020 Mar;18(3):e3000666
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592
Aging 2020 Dec 9;13(2):2575-2592
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, Sun C, Ji J, Yang W, Zhao Z, Mao W
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Chen S, Liu R, Wang Q, Qi Z, Hu Y, Zhou P, Wang Z
Archives of biochemistry and biophysics 2019 May 15;666:73-82
Archives of biochemistry and biophysics 2019 May 15;666:73-82
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
Li Y, Kong R, Chen H, Zhao Z, Li L, Li J, Hu J, Zhang G, Pan S, Wang Y, Wang G, Chen H, Sun B
Aging 2019 Jul 21;11(14):5035-5057
Aging 2019 Jul 21;11(14):5035-5057
Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin.
Zhang Z, Sun C, Zhang L, Chi X, Ji J, Gao X, Wang Y, Zhao Z, Liu L, Cao X, Yang Y, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1541-1546
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1541-1546
RDM1 promotes critical processes in breast cancer tumorigenesis.
Chen Y, Sun Z, Zhong T
Journal of cellular and molecular medicine 2019 Aug;23(8):5432-5439
Journal of cellular and molecular medicine 2019 Aug;23(8):5432-5439
LncRNA lnc-RI regulates homologous recombination repair of DNA double-strand breaks by stabilizing RAD51 mRNA as a competitive endogenous RNA.
Shen L, Wang Q, Liu R, Chen Z, Zhang X, Zhou P, Wang Z
Nucleic acids research 2018 Jan 25;46(2):717-729
Nucleic acids research 2018 Jan 25;46(2):717-729
Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer Cells.
Wang Y, Hu L, Zhang X, Zhao H, Xu H, Wei Y, Jiang H, Xie C, Zhou Y, Zhou F
Journal of Cancer 2017;8(8):1400-1409
Journal of Cancer 2017;8(8):1400-1409
IER5 is involved in DNA Double-Strand Breaks Repair in Association with PAPR1 in Hela Cells.
Yu XP, Wu YM, Liu Y, Tian M, Wang JD, Ding KK, Ma T, Zhou PK
International journal of medical sciences 2017;14(12):1292-1300
International journal of medical sciences 2017;14(12):1292-1300
Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib.
Zhao Q, Guan J, Zhang Z, Lv J, Wang Y, Liu L, Zhou Q, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:165-168
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:165-168
Triptolide induces DNA breaks, activates caspase-3-dependent apoptosis and sensitizes B-cell lymphoma to poly(ADP-ribose) polymerase 1 and phosphoinositide 3-kinase inhibitors.
Guan J, Zhao Q, Lv J, Zhang Z, Sun S, Mao W
Oncology letters 2017 Oct;14(4):4965-4970
Oncology letters 2017 Oct;14(4):4965-4970
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Guan J, Zhao Q, Mao W
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115
Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone.
Song X, Shi Q, Liu Z, Wang Y, Wang Y, Song E, Song Y
Chemical research in toxicology 2016 Dec 19;29(12):2184-2193
Chemical research in toxicology 2016 Dec 19;29(12):2184-2193
5-Azacytidine enhances the radiosensitivity of CNE2 and SUNE1 cells in vitro and in vivo possibly by altering DNA methylation.
Jiang W, Li YQ, Liu N, Sun Y, He QM, Jiang N, Xu YF, Chen L, Ma J
PloS one 2014;9(4):e93273
PloS one 2014;9(4):e93273
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
Groselj B, Kerr M, Kiltie AE
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2013 Sep;108(3):429-33
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2013 Sep;108(3):429-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAD51 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAD51. This antibody recognizes human, mouse, rat antigen. The RAD51 antibody has been validated for the following applications: ELISA, WB analysis.
