BAF692

antibody from Novus Biologicals

Targeting: TNFRSF11A CD265, FEO, LOH18CR1, PDB2, RANK

Western blot (Data presented on provider website)

Antibody Data

Product number

BAF692

Provider

Novus Biologicals

Product name

Goat Polyclonal RANK/TNFRSF11A Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse RANK/TNFRSF11A in Western blots. In this format, approximately 20% cross-reactivity with recombinant human RANK/TNFRSF11A is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Biotin

Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain.

Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, Hoshino M, Imamura T, Akiyama C, Yasuhara R, Mishima K, Maruyama T, Kohda C, Tanaka K, Potempa J, Yasuda H, Baba K, Kamijo R
The Journal of biological chemistry 2014 May 30;289(22):15621-30

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Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment.

Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
Journal of cell science 2012 Jun 15;125(Pt 12):2910-7

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Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.

Wang Y, Lebowitz D, Sun C, Thang H, Grynpas MD, Glogauer M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008 Feb;23(2):260-70