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- Antibody Data
- Antigen structure
- References [2]
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- Immunohistochemistry [1]
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- Product number
- MAB6831-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human RANK/TNFRSF11A Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects recombinant human RANK in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, recombinant mouse (rm) BAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR4, rhDR5, rhEDAR, rmEDAR, rmFas, rhGITR, rhHVEM, rhLymphotoxin beta R, rhNGF R, rhOPG, rmRANK, rhRELT, rhTNF RI, rmTNF RI, rhTNF RII, rhTRAIL R2, rhTRAIL R3, rhTRAIL R4, or rhTROY is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q9Y6Q6- Isotype
- IgG
- Antibody clone number
- 80707
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone.
High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4+ T lymphocytes.
Day KC, Lorenzatti Hiles G, Kozminsky M, Dawsey SJ, Paul A, Broses LJ, Shah R, Kunja LP, Hall C, Palanisamy N, Daignault-Newton S, El-Sawy L, Wilson SJ, Chou A, Ignatoski KW, Keller E, Thomas D, Nagrath S, Morgan T, Day ML
Cancer research 2017 Jan 1;77(1):74-85
Cancer research 2017 Jan 1;77(1):74-85
High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4+ T lymphocytes.
Vernal R, Dutzan N, Hernández M, Chandía S, Puente J, León R, García L, Del Valle I, Silva A, Gamonal J
Journal of periodontology 2006 Oct;77(10):1772-80
Journal of periodontology 2006 Oct;77(10):1772-80
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- RANK/TNFRSF11A in Human Liver. RANK/TNFRSF11A was detected in immersion fixed paraffin-embedded sections of human liver using Mouse Anti-Human RANK/TNFRSF11A Monoclonal Antibody (Catalog # MAB6831) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
