Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881884 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (C-Term), (AA 1478-1506) antibody
- Antibody type
- Polyclonal
- Antigen
- This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 1478-1506
- Antibody clone number
- RB41848
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma.
The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
miR-10b targets Tiam1: implications for Rac activation and carcinoma migration.
Yang W, Lv S, Liu X, Liu H, Yang W, Hu F
Japanese journal of clinical oncology 2010 Nov;40(11):1053-9
Japanese journal of clinical oncology 2010 Nov;40(11):1053-9
The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
Shepherd TR, Klaus SM, Liu X, Ramaswamy S, DeMali KA, Fuentes EJ
Journal of molecular biology 2010 May 21;398(5):730-46
Journal of molecular biology 2010 May 21;398(5):730-46
miR-10b targets Tiam1: implications for Rac activation and carcinoma migration.
Moriarty CH, Pursell B, Mercurio AM
The Journal of biological chemistry 2010 Jul 2;285(27):20541-6
The Journal of biological chemistry 2010 Jul 2;285(27):20541-6
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- TIAM1 Antibody (C-term) (ABIN1881884) western blot analysis in ZR-75-1 cell line lysates (35 μg/lane). This demonstrates the TIAM1 antibody detected the TIAM1 protein (arrow).