ABIN1673359

antibody from antibodies-online

Targeting: DDR2 NTRKR3, TKT, TYRO10

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN1673359

Provider

antibodies-online

Product name

anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human DDR2, different from the related mouse sequence by three amino acids.Immunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Mutations in DDR2 gene cause SMED with short limbs and abnormal calcifications.

Bargal R, Cormier-Daire V, Ben-Neriah Z, Le Merrer M, Sosna J, Melki J, Zangen DH, Smithson SF, Borochowitz Z, Belostotsky R, Raas-Rothschild A
American journal of human genetics 2009 Jan;84(1):80-4

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The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism.

Labrador JP, Azcoitia V, Tuckermann J, Lin C, Olaso E, Mañes S, Brückner K, Goergen JL, Lemke G, Yancopoulos G, Angel P, Martínez C, Klein R
EMBO reports 2001 May;2(5):446-52

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Spondylo-meta-epiphyseal dysplasia (SMED), short limb-hand type: a congenital familial skeletal dysplasia with distinctive features and histopathology.

Borochowitz Z, Langer LO Jr, Gruber HE, Lachman R, Katznelson MB, Rimoin DL
American journal of medical genetics 1993 Feb 1;45(3):320-6