Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- MAB2538 - Provider product page
- Provider
- R&D Systems
- Product name
- Human DDR2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human DDR2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human DDR1 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q16832
- Isotype
- IgG
- Antibody clone number
- 290814
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references TWIST1 induces expression of discoidin domain receptor 2 to promote ovarian cancer metastasis.
Collagen Type 1 Accelerates Healing of Ruptured Fetal Membranes.
Regulation of collagen fibrillogenesis by cell-surface expression of kinase dead DDR2.
Increased expression of discoidin domain receptor 2 is linked to the degree of cartilage damage in human knee joints: a potential role in osteoarthritis pathogenesis.
Grither WR, Divine LM, Meller EH, Wilke DJ, Desai RA, Loza AJ, Zhao P, Lohrey A, Longmore GD, Fuh KC
Oncogene 2018 Mar;37(13):1714-1729
Oncogene 2018 Mar;37(13):1714-1729
Collagen Type 1 Accelerates Healing of Ruptured Fetal Membranes.
Mogami H, Kishore AH, Word RA
Scientific reports 2018 Jan 12;8(1):696
Scientific reports 2018 Jan 12;8(1):696
Regulation of collagen fibrillogenesis by cell-surface expression of kinase dead DDR2.
Blissett AR, Garbellini D, Calomeni EP, Mihai C, Elton TS, Agarwal G
Journal of molecular biology 2009 Jan 23;385(3):902-11
Journal of molecular biology 2009 Jan 23;385(3):902-11
Increased expression of discoidin domain receptor 2 is linked to the degree of cartilage damage in human knee joints: a potential role in osteoarthritis pathogenesis.
Sunk IG, Bobacz K, Hofstaetter JG, Amoyo L, Soleiman A, Smolen J, Xu L, Li Y
Arthritis and rheumatism 2007 Nov;56(11):3685-92
Arthritis and rheumatism 2007 Nov;56(11):3685-92
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- DDR2 in Human Lung. DDR2 was detected in immersion fixed paraffin-embedded sections of human lung using 25 µg/mL Mouse Anti-Human DDR2 Monoclonal Antibody (Catalog # MAB2538) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific labeling was localized to to cells in connective tissue. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.