ABIN357125

antibody from antibodies-online

Targeting: KCNIP3 CSEN, DREAM, KCHIP3

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN357125

Provider

antibodies-online

Product name

anti-Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (AA 1-30), (N-Term) antibody

Antibody type

Polyclonal

Description

Protein GChromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 1-30, N-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C fore month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3.

Choi EK, Miller JS, Zaidi NF, Salih E, Buxbaum JD, Wasco W
Molecular and cellular neurosciences 2003 Jul;23(3):495-506

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Reduced expression of calsenilin/DREAM/KChIP3 in the brains of kainic acid-induced seizure and epilepsy patients.

Hong YM, Jo DG, Lee MC, Kim SY, Jung YK
Neuroscience letters 2003 Apr 3;340(1):33-6

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DREAM is a critical transcriptional repressor for pain modulation.

Cheng HY, Pitcher GM, Laviolette SR, Whishaw IQ, Tong KI, Kockeritz LK, Wada T, Joza NA, Crackower M, Goncalves J, Sarosi I, Woodgett JR, Oliveira-dos-Santos AJ, Ikura M, van der Kooy D, Salter MW, Penninger JM
Cell 2002 Jan 11;108(1):31-43

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PKA modulation of Kv4.2-encoded A-type potassium channels requires formation of a supramolecular complex.

Schrader LA, Anderson AE, Mayne A, Pfaffinger PJ, Sweatt JD
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10123-33

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Calsenilin enhances apoptosis by altering endoplasmic reticulum calcium signaling.

Lilliehook C, Chan S, Choi EK, Zaidi NF, Wasco W, Mattson MP, Buxbaum JD
Molecular and cellular neurosciences 2002 Apr;19(4):552-9